Results 171 to 180 of about 3,869,309 (345)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Serum-mediated Immune Cellular Responses to Brucella melitensis IV. Infection of Macrophages Under Anaerobic Conditions [PDF]

, 1969
D. J. Ralston, Sanford S. Elberg
openalex   +1 more source

Mediation [PDF]

Baylor University Medical Center Proceedings, 2003
openaire   +2 more sources

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Adverse childhood experiences, basic psychological needs, and adolescent affective distress: Revisiting the buffering role of resilience factors. [PDF]

J Res Adolesc
Zhou K, Zhu X, Lu C, Yang Y, Chen S.
europepmc   +1 more source

Ferredoxin mediated hydrogen formation from NADPH in a cell‐free system of Clostridium kluyveri [PDF]

, 1969
Kurt Jungermann, Rudolf K. Thauer, E. Rupprecht, Christian Ohrloff, K. Decker   +4 more
openalex   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

David Dean Shulman. Tamil: A Biography. pp. 416. The Belknap Press of Harvard University Press, Cambridge, Massachusetts,and London 2016, ISBN 978-0674059924. $ 35 / £ 28.95 / € 31.50

Cracow Indological Studies, 2020
Olga Vecherina
doaj   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

Molecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel R. Teixeira, Paula Paulo   +5 more
wiley   +1 more source

High-dimensional causal mediation analysis by partial sum statistic and sample splitting strategy in imaging genetics application. [PDF]

Bioinformatics
Chang HC, Fang Y, Gorczyca MT, Batmanghelich K, Tseng GC.   +4 more
europepmc   +1 more source