Early intracellular events in the replication of T4 phage DNA, IV. Host-mediated single-stranded breaks and repair in ultraviolet-damaged T4 DNA. [PDF]
Andrzej W. Kozinski, Z Lorkiewicz
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Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Inferences and effect sizes for direct, indirect, and total effects in continuous-time mediation models. [PDF]
Pesigan IJA, Russell MA, Chow SM.
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Studies on the mechanism of estrogen-mediated tissue differentiation: regulation of nuclear transcription and induction of new RNA species. [PDF]
Bert W. O’Malley, William McGuire
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In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Multi-omics mediation pipeline reveals differential pathways of maternal SNPs affecting newborn adiposity outcomes. [PDF]
Gill NP, Kuang A, Scholtens DM.
europepmc +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Cardiovascular disease as a mediator in the relationship between lifestyle risk factors and cognitive outcomes: a scoping review. [PDF]
Hensel ALJ +22 more
europepmc +1 more source
Mechanism of R factor-mediated chloramphenicol resistance [PDF]
William V. Shaw, Joel Unowsky
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