Results 51 to 60 of about 1,783,352 (358)
Jasmonate (JA) signaling plays an important role in regulating both plant defense and development. We have recently reported that the phytochrome and flowering time1 (PFT1) gene, which encodes the mediator25 subunit of the plant Mediator complex, is a key regulator of JA regulated transcription.
Kidd, Brendan N.+4 more
openaire +3 more sources
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali+3 more
wiley +1 more source
Mapping Perspectives on the EU as Mediator [PDF]
Research on the European Union’s role as a meditator is nascent. It predominantly focuses on case studies or is cursorily embedded within wider research on the European Union (EU) as a crisis manager. Moreover, there is a significant disconnect between
Haastrup, Toni
core
Die Leitfragen dieses Beitrags beziehen sich auf Ziele und Auswirkungen der Einführung von Mediation in eine Schulkultur der Dominanz, des Wettbewerbs und der Auswahl. Zusätzlich soll die Notwendigkeit der Verbindung von Konfliktlösung mit Organisationsentwicklung und der Einführung eines ethischen Konsens gezeigt werden, um nachhaltige Ergebnisse in ...
openaire +3 more sources
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Understanding people’s attitudes toward conciliatory policies in territorial interethnic conflicts is important for a peaceful conflict resolution. We argue that ingroup identification in combination with the largely understudied territorial ownership ...
Nora Storz+2 more
doaj +1 more source
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Distinguishing anomaly mediation from gauge mediation with a Wino NLSP [PDF]
A striking consequence of supersymmetry breaking communicated purely via the superconformal anomaly is that the gaugino masses are proportional to the gauge beta functions. This result, however, is not unique to anomaly mediation. We present examples of `
Kribs, Graham D.
core +2 more sources
Immersive technologies cover a multitude of emerging technologies focused on immersion, virtualization and interactivity. They cover several categories including three main ones, namely virtual reality (VR), augmented reality (AR) and mixed reality (MR),
Loubna FOUINNA, Hassan EL OUAZZANI
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source