Results 191 to 200 of about 716,628 (306)

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

The impact of physical activity on social anxiety among college students: an analysis of the chain mediation effect of family support and self-efficacy. [PDF]

PeerJ
Yang B, Yang X, Fan Z, Liu C, Zheng Z.
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

"Dr. Google" consultation and health anxiety among primary healthcare patients: The mediation effect of health literacy. [PDF]

PLoS One
Pasay-An E, Alalawi RH, Shanmugam SR, Alshammari SA, Alreshidi MS, Alkubati S, Alrashidi N, Pangket P, Benjamin LS, Gonzales F, Sacgaca L, Mostoles R.   +11 more
europepmc   +1 more source

Phonon-mediated Casimir effect

, 2019
The Casimir interaction is the fundamental physical phenomenon which emerges due to modification of vacuum fluctuations by boundaries in a confined area of space. It arises in many fields of physics, including condensed matter. Recently, substantial interest in the Casimir effect has revived as a result of the significant progress in the experimental ...
openaire   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

The effect of exercise intervention on prosocial behavior in junior high school students: the chain mediation effect of empathy and interpersonal relationships. [PDF]

Front Psychol
Tang S, Lu T, Chen H, Tao B, Yan J.
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

The relationship between cognitive function and quality of life in older hypertension patients: a parallel mediation effect of frailty and medication discrepancies. [PDF]

BMC Geriatr
Zhou L, Chen Z, Li X, Wu Y, Guan H, Yin W, Sun K, Yu Q.   +7 more
europepmc   +1 more source

SUMOylation mediates brassinosteroid effects [PDF]

Nature Reviews Molecular Cell Biology, 2014
openaire   +1 more source