Results 41 to 50 of about 9,734,843 (296)

Sleep Quality Mediates the Association Between Cerebral Small Vessel Disease Burden and Frailty: A Community-Based Study

Frontiers in Aging Neuroscience, 2021
Background: Physical frailty is a common problem among older adults which usually leads to adverse health outcomes. The imaging markers of cerebral small vessel disease (CSVD) are associated with frailty, but the underlying mechanisms remain unclear. The
Jing Zhao, Wensheng Qu, Xirui Zhou, Yinping Guo, Yi Zhang, Lingshan Wu, Zhiyuan Yu, Hao Huang, Xiang Luo   +8 more
doaj   +1 more source

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Effect of mediators on coronary circulation

European Heart Journal, 1991
A number of vasoactive mediators have been identified in plasma and in the heart. Some of them may be liberated in inflammatory heart disease. The action of mediators on coronary vasculature in various animal models and their potential role in inflammatory heart disease is reviewed. Their role in patients remains to be determined.
Ertl, G, Bauer, B, Neubauer, S, Schorb, W, Kochsiek, K   +4 more
openaire   +3 more sources

Bayesian Inference for the Causal Effect of Mediation [PDF]

Biometrics, 2012
Summary We propose a nonparametric Bayesian approach to estimate the natural direct and indirect effects through a mediator in the setting of a continuous mediator and a binary response. Several conditional independence assumptions are introduced (with corresponding sensitivity parameters) to make these effects identifiable from the observed data.
Daniels, Michael J., Roy, Jason A., Kim, Chanmin, Hogan, Joseph W., Perri, Michael G.   +4 more
openaire   +3 more sources

Relationship among number of close friends, subclinical geriatric depression, and subjective cognitive decline based on regional homogeneity of functional magnetic resonance imaging data

Frontiers in Aging Neuroscience, 2022
The relationship between geriatric depression and dementia has been widely debated, and the neurological mechanisms underlying subjective cognitive decline (SCD) associated with social relationships remain elusive.
Zhao Zhang, Guangfei Li, Guangfei Li, Zeyu Song, Ying Han, Xiaoying Tang   +5 more
doaj   +1 more source

Ewing Sarcoma in Infants and Children Under 2 Years of Age: A French Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma, the second most common primary bone cancer in children, requires intensive treatment that may lead to significant long‐term sequelae, particularly in infants. We retrospectively analyzed data from 1621 French patients treated between 1988 and 2015 within the EW88/93/97 or EE99 trials, focusing on 17 infants diagnosed before 24 ...
Elodie Verdier, Nathalie Cozic, Marie‐Dominique Tabone, Gaelle Pierron, Perrine Marec‐Berard, Sarah Winter, Gabriel Revon‐Rivière, Cyril Lervat, Dominique Plantaz, Marie‐Pierre Castex, Gregory Guimard, Estelle Thebaud, Stephanie Proust, Laure Saumet, Natacha Entz‐Werle, Sophie Taque, Cécile Vérité, Marta Jimenez, Nathalie Gaspar   +18 more
wiley   +1 more source

The Effect of Mediators' Qualities and Strategies on Mediation Outcomes [PDF]

Relations industrielles, 2005
This study utilizes discriminant analysis to determine if the characteristics of mediators and the strategies they employ predict the success of mediation in resolving impasses in the public sector in lowa. The data were obtained from questionnaires administered to management and union negotiators in the 214 impasses reported in lowa during 1986 ...
Dilts, David A., Karim, Ahmad
openaire   +1 more source

Professional identity and job performance among vocational education teachers—a chain mediation model of leader–member exchange and self-efficacy, with job crafting as a moderator

Frontiers in Psychology
PurposeThis research explores the effect of professional identity (PI) on the job performance (JP) of vocational education and training (VET) teachers, with a particular focus on the sequential mediation effects of leader-member exchange (LMX) and self ...
Ying Zhou, Zonglin Zhong
doaj   +1 more source

Potential Value of Serum Lipid in the Identication of Postoperative Delirium Undergoing Knee/Hip Arthroplasty: The Perioperative Neurocognitive Disorder and Biomarker Lifestyle Study

Frontiers in Psychiatry, 2022
ObjectiveWe aimed to investigate the relationship between preoperative lipid level and postoperative delirium (POD) and explore whether lipid’s effect on POD is mediated by POD core protein.MethodsA total of 635 patients who were planned to undergo knee ...
Yanan Lin, Xiaoyan Peng, Xu Lin, Xiyuan Deng, Fanghao Liu, He Tao, Rui Dong, Bin Wang, Yanlin Bi   +8 more
doaj   +1 more source

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source