Results 71 to 80 of about 9,734,843 (296)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Examining school based mediation: a literature review [PDF]

open access: yes, 2003
Plan BThis paper reviews the existing literature on school based mediation programs to answer the questions: What is school based mediation and what are the effects of school based mediation?
Murray, Barbara A.
core  

Mediation today: The art of founding a mediation clinic [PDF]

open access: yes, 2021
A knowledge exchange paper entitled Mediation Today: The Art of Founding a Mediation Clinic, to raise awareness, provide guidance and assistance for those law schools proposing to set up and establish a mediation clinic. Presented on 6th February 2021 at
Waters, B.
core  

A chain mediation model reveals the association between parental mediation and smartphone addiction of Chinese adolescents

open access: yesScientific Reports
The family plays an immensely crucial role in the development of adolescents, significantly influencing their behavioral patterns. To explore the impact mechanism of the parental mediation (active mediation, restrictive mediation, and parental monitoring)
Yan Chen   +4 more
doaj   +1 more source

Demographic Change and Commons Governance: Examining the Impacts of Rural Out-Migration on Public Open Spaces in China Through a Social–Ecological Systems Framework

open access: yesLand
Rapid urbanization in China has driven substantial rural population out-migration, raising concerns about its implications for the governance of land commons in villages. While existing studies have acknowledged the effects of migration on rural resource
Xuerui Shi   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Investigating the Mediating Role of Cardiometabolic Traits in the Causal Link Between SHBG Levels and Stroke Risk via Network Mendelian Randomization

open access: yesCurrent Issues in Molecular Biology
The causal nature of sex hormone-binding globulin (SHBG) in the pathogenesis of stroke remains uncertain. We explored whether SHBG levels are causally associated with stroke via cardiometabolic traits.
Peijiang Pan, Hao Liang, Mingli Li
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

AFRICAN-STYLE MEDIATION AND WESTERN-STYLE DIVORCE AND FAMILY MEDIATION: REFLECTIONS FOR THE SOUTH AFRICAN CONTEXT [PDF]

open access: yes, 2012
Both Western-styled mediation and African-styled mediation are practised in South Africa. Each of these models is applied in specific social contexts.
Boniface, AE, AE Boniface, Boniface, A E
core   +1 more source

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