Results 241 to 250 of about 1,219,522 (300)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

PsAvh109 suppresses SA-triggered immunity by mimicking TPL function to disrupt mediator complex assembly. [PDF]

Nat Commun
Tan X, Sun Y, Qi Z, Miao Y, Liu Z, Wan Y, Hou X, Li H, Li W, Chen Y, Xu Q, Wang Q.   +11 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Active control of forward/backward charge transfer in Z-scheme water splitting: manipulating electrostatic affinity/repulsion between photocatalyst surface and electron mediator. [PDF]

Chem Sci
Itagaki R, Nakada A, Suzuki H, Tomita O, Abe R.   +4 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Life-course influence of birthweight and subsequent pathways on healthy aging: a Mendelian randomization study. [PDF]

BMC Med
Kong L, Dou C, Ye C, Liu D, Chen M, Zheng J, Xu M, Xu Y, Li M, Zhao Z, Lu J, Chen Y, Ning G, Wang W, Bi Y, Liu R, Wang T.   +16 more
europepmc   +1 more source

Evaluating Methods for High-Dimensional Mediation in Metabolomics Data. [PDF]

Environ Sci Technol
Hoffman SS, Liang D, Dunlop A, Everson T, Gaskins AJ, Jones DP, Hüls A, Marcus M, Naimi AI.   +8 more
europepmc   +1 more source

Pain, sleep, fatigue, and health-related quality of life in pediatric sickle cell disease: a serial multiple mediator analysis. [PDF]

Front Pain Res (Lausanne)
Varni JW.
europepmc   +1 more source

Interpreting Blood Transfusion in Hip Fracture Surgery: Marker of Severity Rather Than Mediator of Harm? [Letter]. [PDF]

J Blood Med
Ahmad A, Harris BHL, Fertleman MB, Koizia LJ.   +3 more
europepmc   +1 more source

Genetic evidence for potential molecular mediators underlying the causal relationship between obesity and breast cancer: a two-step, two-sample Mendelian randomization study. [PDF]

BMC Cancer
Hao Y, Jiang X, Xiao J, Fan M, Wu X, Liao J, Zhao X, Feng W, Qi H, Li J.   +9 more
europepmc   +1 more source