Results 141 to 150 of about 4,197,094 (329)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
História, Ciências, Saúde: ManguinhosResumo Discute como funciona um projeto de desenvolvimento com foco na saúde num cenário de emergência e os efeitos dele decorrentes para além dos propostos como objetivos.
Uliana Esteves
doaj +1 more source
Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators
Nature reviews. Immunology, 2008 C. Serhan, Chia Nan, T. Dyke
semanticscholar +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
SocietyPandeglang Regency is home to numerous potential tourism villages dispersed across various locations; however, their management remains fragmented and lacks comprehensive stakeholder involvement.
Neka Fitriyah +2 more
doaj +1 more source
Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities
Nature Reviews Cardiology, 2019 M. Bäck +4 more
semanticscholar +1 more source
Negotiation Journal, 1993 TheInterim Guidelines for Selecting Mediators promote a mythology that is broader and already more effective than the specific screening device created by the guidelines is likely to be. That mythology has been quite successful in generating support for the institutionalization of mediation and the establishment of both a market and an occupation in ...
openaire +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source