Results 211 to 220 of about 4,197,094 (329)

Mediation analysis with time varying exposures and mediators

Journal of The Royal Statistical Society Series B-statistical Methodology, 2017
T. VanderWeele, E. T. Tchetgen Tchetgen
semanticscholar   +1 more source

Evaluating Methods for High-Dimensional Mediation in Metabolomics Data. [PDF]

Environ Sci Technol
Hoffman SS, Liang D, Dunlop A, Everson T, Gaskins AJ, Jones DP, Hüls A, Marcus M, Naimi AI.   +8 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Fibroblasts as Immunological Sentinels in Cutaneous Inflammation: A Review. [PDF]

J Clin Med
Quan T.
europepmc   +1 more source

Mediated realities [PDF]

Tidsskrift for Den norske legeforening, 2018
openaire   +2 more sources

Mediators of vasopressin induced natriuresis in cirrhosis [PDF]

, 1989
Gerbes, Alexander L.
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

MSC administration resolves experimental acute gout increasing specialized pro-resolving mediators synthesis through a super-induction of prostaglandin E₂. [PDF]

Stem Cell Res Ther
Bermejo-Álvarez I, Vázquez C, Irigaray-Moreno A, Quevedo-Romero I, Mediero A, Herrero-Beaumont G, Largo R.   +6 more
europepmc   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

A rechargeable lithium–oxygen battery with dual mediators stabilizing the carbon cathode

Nature Energy, 2017
Xiangwen Gao, Yuhui Chen, L. Johnson, Zarko P. Jovanov, P. Bruce   +4 more
semanticscholar   +1 more source