Results 71 to 80 of about 4,197,094 (329)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Mediator Interactions in Acute Respiratory Distress Syndrome
Общая реаниматология, 2007 The review of literature covers the interaction of numerous mediators that are initiators and major motive forces of the occurrence and development of acute respiratory distress syndrome (ARDS). The major mediator families include cytokines, mediators of
K. A. Pavlov +3 more
doaj +1 more source
Extracellular histones are major mediators of death in sepsis
Nature Medicine, 2009 Hyperinflammatory responses can lead to a variety of diseases, including sepsis. We now report that extracellular histones released in response to inflammatory challenge contribute to endothelial dysfunction, organ failure and death during sepsis.
Jun Xu +9 more
semanticscholar +1 more source
Beyond conflict resolution: socio-emotional learning in student mediators [PDF]
, 2019 Introducción. En los últimos años son muchos los centros educativos que han introducido la mediación entre sus actividades. Sin embargo, la evaluación del servicio es escasa y se suele realizar teniendo en cuenta los acuerdos alcanzados y no el ...
Fernández-Baena, Javier +1 more
core +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Cross-genetic determination of maternal and neonatal immune mediators during pregnancy. [PDF]
, 2018 BACKGROUND:The immune system plays a fundamental role in development during pregnancy and early life. Alterations in circulating maternal and neonatal immune mediators have been associated with pregnancy complications as well as susceptibility to ...
Ashwood, Paul +9 more
core
Sestrins are evolutionarily conserved mediators of exercise benefits. [PDF]
, 2020 Exercise is among the most effective interventions for age-associated mobility decline and metabolic dysregulation. Although long-term endurance exercise promotes insulin sensitivity and expands respiratory capacity, genetic components and pathways ...
Brooks, Susan V +14 more
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Redox Mediator: A New Strategy in Designing Cathode for Prompting Redox Process of Li–S Batteries
Advanced Science, 2019 The multistep redox reactions of lithium–sulfur batteries involve undesirably complex transformation between sulfur and Li2S, and it is tough to spontaneously fragmentate polysulfides into shorter chains Li2S originating from the sluggish redox kinetics ...
Xian Wu +9 more
doaj +1 more source
In vitro effect of canine hyperimmune sera on TNFa activity [PDF]
, 2006 [Introduction]: Septic shock in dogs is caused by cardiovascular and vasomotor failure associated with an uncontrolled intrinsic release of inflammatory mediators [1–5].
Kotiw, Michael +3 more
core +2 more sources