Results 141 to 150 of about 314,862 (218)

Design of Safe and Efficient Adenine Base Editors via Protein Language Model Screening for Osteoarthritis Treatment. [PDF]

Adv Sci (Weinh)
Yao J, Chen D, Zhang Z, Ren J, Zhao C, Wang S, Shang M, Jiang D, Li Y, Tang S, Li K, Zhang X, Wang X.   +12 more
europepmc   +1 more source

Protein Corona Formation on Soft Nanocarriers Under Biomimetic Circulatory Flow

Advanced Materials Interfaces, EarlyView.
A biomimetic venous circulation system is developed to study protein corona formation on soft nanocarriers under physiological shear. Liposomes, PLGA nanoparticles, and lipid‐polymer hybrid nanoparticles acquire largely shared but material‐dependent protein coronas that alter surface properties and suppress cellular uptake, highlighting the importance ...
Anamarija Nikoletić, Dominik Simon Müller, Timon Flathmann, Jakob Steuer, Evangelos Natsaridis, Chiara Candino, Abdullah Kahraman, Oya Tagit   +7 more
wiley   +1 more source

Sequence Display enables large-scale sequence-activity datasets for rapid protein evolution. [PDF]

Nat Biotechnol
Cheng L, Zheng X, Jiang SJ, Hu Y, Liu Y, Yang K, Rui J, Ding H, Zhang M, Yuan T, Lu Q, Ye H, Li CL, Guo Y, Tian Z, Qin A, Zhou B, Yang KK, Huang X, Xiao H.   +19 more
europepmc   +1 more source

Additive‐Manufactured, Multifunctional Bioreactor Technology for Dynamic Culture of 3D Bioprinted Tissue Models

Advanced Materials Technologies, EarlyView.
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger, Johann Schorzmann, Hsuan‐Heng Lu, Muhammad Osama, Julian Bauer, Michael Haug, Oliver Friedrich, Aldo R. Boccaccini, Frank Döpper, Sahar Salehi   +9 more
wiley   +1 more source

Correction: Nucleobase-containing compounds evoke behavioural, olfactory, and transcriptional responses in model fishes

FACETS, 2018
Angela L. Shamchuk, Brian J. Blunt, Danielle D. Lyons, Mo Qi Wang, Anastasia Gasheva, Carlie R. Lewis, Kirsten Tomlin, E. Starr Hazard, Gary Hardiman, Keith B. Tierney   +9 more
doaj   +1 more source

Correction of the molecular phenotype of X-linked Dystonia-Parkinsonism reveals a non-canonical function of BRD4. [PDF]

Nat Commun
Capponi S, Ehret S, Camgöz Z, Gather F, Vaine CA, Özyerli-Göknar E, Follo M, Bragg DC, Vogel T, Timmers HTM.   +9 more
europepmc   +1 more source

At Home Detection of Ovarian Health Biomarker in Menstruation Blood

Advanced Materials Technologies, EarlyView.
A lateral flow assay enables the detection of anti‐Müllerian hormone directly in unprocessed menstrual blood using silica‐gold nanoshells and smartphone‐assisted machine learning analysis. The platform supports decentralized, user‐operated testing in wearable and dipstick formats, highlighting the potential of menstrual blood as a non‐invasive matrix ...
Lucas Dosnon, Thomas Rduch, Salma Sherif Azer, Inge K. Herrmann   +3 more
wiley   +1 more source

Protocol for massively parallel RNA assay combined with immunoprecipitation for high-throughput analysis of RNA-protein interactions in cells. [PDF]

STAR Protoc
Lee YH, Rinn JL, Hwang T.
europepmc   +1 more source

Spheroid‐On‐A‐Drop: A Modular Droplet Microfluidics Platform

Advanced Materials Technologies, EarlyView.
The proposed Spheroid‐on‐a‐Drop platform represents a reproducible and tunable platform for the fabrication of biocompatible GelMA‐based microgels, able to support controlled 3D tumor spheroid culture. Its precise control over droplet dynamics and cell distribution paves the way for advanced applications in tissue modeling, drug screening, and ...
A. Fergola, V. Vighetto, G. Mesiano, A. Cosola, S. L. Marasso, M. Cocuzza, C. F. Pirri, L. Napione, F. Frascella   +8 more
wiley   +1 more source

Protocol for isolating cells from a single cryopreserved gastrointestinal endoscopic biopsy for single-cell RNA sequencing. [PDF]

STAR Protoc
Horowitz D, Rusbuldt J, Tomsho L, Lee T, Sohn K, Kannan A, Ruane D.   +6 more
europepmc   +1 more source