Results 91 to 100 of about 20,373,278 (386)

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Evalution of Frequency of Hirsutism in Female Students of Hamadan University of Medical Sciences

پزشکی بالینی ابن سینا, 1997
Objective: Evalution of frequency of hirsutism in female students of Hamadan University of Medical Sciences in 1995-1996. Population:  700 female students (Married & Nonmarried ) of Hamadan University of Medical Sciences in 1995-1996. Method: Providing
Amaneh Yazdanfar, Zahra Beyhaghi, Nahid Manoochehrian   +2 more
doaj  

Medical Hierarchy and Medical Garb

AMA Journal of Ethics, 2013
If medical garb reinforces a hierarchical barrier to cooperation in the clinic, it is a failure of interprofessional training in collaborative practice, not an indictment of the utility of role differentiation.
Aliye Runyan, Jason W Wilson, Anna Willieme, Daniella M Schocken   +3 more
openaire   +2 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Exploration of mental health problems in association with health-promoting lifestyle profile in Iranian medical students: A cross-sectional study

Journal of Education and Health Promotion, 2020
OBJECTIVE: The aim was to explore the relationship between mental health problems (MHPs) and health-promoting lifestyle (HPL) in the medical students. METHODS: This cross-sectional study was carried out on medical students in 2017 at Semnan University of
Nilufar Safaie, Sara Ketabi, Naimossadat Kia, Majid Mirmohammadkhani, Mohammad Reza Moonesan, Fatemeh Paknazar   +5 more
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Aerobics health as means of increasing somatic health of students of special medical group

Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2013
We prove the feasibility of employment by improving aerobic low intensity (LowImpact - heart rate in the range 128-140 beats / min, or 60-74% of HR max) with students of special medical groups with disabilities cardiovascular system.
M.M. Pivneva, O.G. Rumba
doaj  

Knowledge, practices and attitudes toward volunteer work in an influenza pandemic: cross-sectional study with Peruvian medical students

Medwave, 2015
INTRODUCCIÓN La reducción crítica en el personal de salud ante situaciones de desastre o epidemia como una pandemia de influenza podría requerir la necesidad de incluir estudiantes voluntarios.
10.5867/medwave.2015.04.6136, Julio Maquera-Afaray, Patricia J. García, César Cárcamo   +3 more
doaj   +1 more source