Results 271 to 280 of about 17,427,068 (314)

Retraction Note: Diabetes mellitus and risk of incident dementia in APOE ɛ4 carriers: an updated meta-analysis. [PDF]

BMC Neurosci
Rashtchian A, Etemadi MH, Asadi E, Binaei S, Abbasi M, Bayani M, Izadi E, Sadat-Madani SF, Naziri M, Khoshravesh S, Shirani M, Anar MA, Deravi N.   +12 more
europepmc   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Developing evaluation index system for "new medicine" construction in Chinese medical schools-meta-ethnography and Delphi-AHP approach. [PDF]

Front Med (Lausanne)
Zheng D, Hassan NC, Ghazali N, Chai Y, Zhang D, Lyu W.   +5 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Gaps in artificial intelligence research for rural health in the United States: a scoping review. [PDF]

J Am Med Inform Assoc
Brown KE, Davis SE.
europepmc   +1 more source

Library\u27s Mobile Applications; March eScience Lecture, Vol. 10, (3) [PDF]

, 2012
Texas Medical Center Library
core   +1 more source

Characterising Informal Care in Older Individuals Receiving Long-Term Home Care Support: A National Epidemiological Study. [PDF]

Australas J Ageing
Eshetie TC, Cuthbert AR, Sluggett JK, Yu S, Dawkins C, Schulze M, Caughey GE, Inacio MC.   +7 more
europepmc   +1 more source

Editorial Expression of Concern: Trends in chronic kidney disease mortality among patients with systemic lupus erythematosus: a U.S. population-based study (1999-2020). [PDF]

BMC Nephrol
Qadri M, Rahman SU, Javaid H, Bhandari K, Syed R, Khan AA, Bacha Z, Noor R, Filal M.   +8 more
europepmc   +1 more source

Effect of medical and surgical therapy on intraocular pressure fluctuations among glaucoma patients in the University of Ilorin Teaching Hospital: A comparative clinical study. [PDF]

BMC Ophthalmol
Obajolowo TS, Yusuf IA, Ambali AO, Tota-Bolarinwa BT, Aderounmu AB, Olatunji FO.   +5 more
europepmc   +1 more source