Results 191 to 200 of about 2,779,055 (335)

Understanding Barriers to Providing Medical Aid in Dying (MAID) to Out-of-State Residents [PDF]

open access: yes
Act 39 was established in May 2013 to provide individuals with documented terminal conditions the option of MAID (Medical Aid in Dying). Access to this care is now available to out-of-state residents who can establish care with a Vermont provider so long
Rattu, Gurkiranjit K
core   +1 more source

MediTOD: An English Dialogue Dataset for Medical History Taking with Comprehensive Annotations [PDF]

open access: yesarXiv
Medical task-oriented dialogue systems can assist doctors by collecting patient medical history, aiding in diagnosis, or guiding treatment selection, thereby reducing doctor burnout and expanding access to medical services. However, doctor-patient dialogue datasets are not readily available, primarily due to privacy regulations.
arxiv  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Drawing a Line Between Killing and Letting Die: The Law, and Law Reform, on Medically Assisted Dying [PDF]

open access: yes, 1993
Traditional medical ethics and law draw a sharp distinction between allowing a patient to die and helping her die. Withholding or withdrawing life sustaining treatment, such as by abating technological nutrition, hydration or respiration, will cause ...
Gostin, Lawrence O.
core   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

CopilotCAD: Empowering Radiologists with Report Completion Models and Quantitative Evidence from Medical Image Foundation Models [PDF]

open access: yesarXiv
Computer-aided diagnosis systems hold great promise to aid radiologists and clinicians in radiological clinical practice and enhance diagnostic accuracy and efficiency. However, the conventional systems primarily focus on delivering diagnostic results through text report generation or medical image classification, positioning them as standalone ...
arxiv  

Interplay of integrins and selectins in metastasis

open access: yesMolecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva   +2 more
wiley   +1 more source

MediCLIP: Adapting CLIP for Few-shot Medical Image Anomaly Detection [PDF]

open access: yesarXiv
In the field of medical decision-making, precise anomaly detection in medical imaging plays a pivotal role in aiding clinicians. However, previous work is reliant on large-scale datasets for training anomaly detection models, which increases the development cost.
arxiv  

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Developing a survey to measure nursing students’ knowledge, attitudes and beliefs, influences, and willingness to be involved in Medical Assistance in Dying (MAiD): a mixed method modified e-Delphi study

open access: yesBMC Nursing
Background Medical Assistance in Dying (MAiD) was legalized in Canada in 2016. Canada’s legislation is the first to permit Nurse Practitioners (NP) to serve as independent MAiD assessors and providers. Registered Nurses’ (RN) also have important roles in
Jocelyn Schroeder   +4 more
doaj   +1 more source

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