Results 131 to 140 of about 2,618,941 (299)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Medical Sciences Library

open access: yes
Medical Sciences Library offers resources and services to support the teaching, research, and clinical programs of the College of Veterinary Medicine and Biomedical Sciences, the Texas A&M Health Science Center, and the College of Agriculture and ...

core   +1 more source

Prevalence of Diabetic-nephropathy in Children and Adolescents with Type-one- Diabetes Mellitus: A Recent Perspective

open access: yesJournal of Medicine in Scientific Research
Background Among the most important microvascular complications in Type-one-Diabetes Mellitus (T-1-DM) in adolescents and children, Diabetic-nephropathy (DN) stands high.
Randa Mohamed Darwish   +3 more
doaj   +1 more source

Bibliometric profile of the African Academy of Sciences medical and health sciences fellows. [PDF]

open access: yesPan Afr Med J, 2021
Balogun J   +4 more
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

COVID-19 Knowledge, Attitudes, and Practices of United Arab Emirates Medical and Health Sciences Students: A Cross Sectional Study [PDF]

open access: yesPLoS One, 2021
Baniyas N   +9 more
europepmc   +2 more sources

What is the association between iron deficiency anemia and the frequency or severity of febrile seizures in children under the age of 5?

open access: yesJournal of Medicine in Scientific Research
Background and Aim Febrile seizures (FS) are a common type of convulsion in young children and are frequently associated with fever in the absence of a central nervous system infection.
Rehab Fawzy Abdel Mohsen Soliman   +7 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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