Results 51 to 60 of about 94,048 (260)

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

Advanced Materials, EarlyView.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi, Pere Català, Gabriel Größbacher, Paulina Nuñez Bernal, Olaf Nijssen, Sammy Florczak, Wilco Nijenhuis, Nuria Crusellas‐Villorbina, Bram Nijhoff, Paul Delrot, Jos Malda, Andreas Hierholzer, Martin Fussenegger, Lukas C. Kapitein, Riccardo Levato   +14 more
wiley   +1 more source

Seasonal distribution and faunistic of ticks in the Alashtar county (Lorestan Province), Iran

The Pan African Medical Journal, 2017
INTRODUCTION: Ticks are non-permanent obligate parasites that have considerable medical-veterinary and zoonosis importance. In this regard a study designed to investigate the distribution and fauna of ticks in the Alashtar county in Iran from April and ...
Behroz Davari, Firoz Nazari Alam, Hassan Nasirian, Mansour Nazari, Mohammad Abdigoudarzi, Aref Salehzadeh   +5 more
doaj   +1 more source

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

Advanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung, Victor Tsao, Alina D Peshkova, Oscar A. Marcos‐Contreras, Kim Ha, Brian M Dulmovits, Nkemdilim Okoli, Anvi Sinha, Gennadiy Fonar, Rong Qiu, Rolf D Bates, Janelle Yeboah, Carson Shalaby, Tyler Truex, Soomin Jeong, Edna C Hardeman, Peter W Gunning, Vladimir R Muzykantov, Jacob W Myerson, Christopher S Thom   +19 more
wiley   +1 more source

Vaccination and non-antibiotic strategies for effective control of multidrug-resistant Salmonella bacteria of medical and veterinary importance

Letters in Animal Biology
With conservatively estimated millions of illnesses and deaths each year, most of which are caused by food contamination, Salmonella is now a threat and economic cost to the world.
Ahmed Shandookh Hameed, Jannat Riaz, Ahmed Raheem Rayshan, Areej Salih Saihood Al-Kinani, Anwar Saleh Saihood Al-Kinani, Ammar Younas, Rawaa Najim Alkhamessi, Mustafa Jawad Kadham, Mirza Muhammad Haris, Ayesha Bintay Farooq, Silla Ambrose, Arslan Muhammad Ali Khan   +11 more
doaj   +1 more source

Parasites and vector-borne diseases disseminated by rehomed dogs

Parasites & Vectors, 2020
The Companion Vector-Borne Diseases (CVBD) World Forum is a working group of leading international experts who meet annually to evaluate current scientific findings and future trends concerning the distribution, pathogenesis, clinical presentation ...
Ian Wright, Frans Jongejan, Mary Marcondes, Andrew Peregrine, Gad Baneth, Patrick Bourdeau, Dwight D. Bowman, Edward B. Breitschwerdt, Gioia Capelli, Luís Cardoso, Filipe Dantas-Torres, Michael J. Day, Gerhard Dobler, Lluis Ferrer, Luigi Gradoni, Peter Irwin, Volkhard A. J. Kempf, Barbara Kohn, Friederike Krämer, Michael Lappin, Maxime Madder, Ricardo G. Maggi, Carla Maia, Guadalupe Miró, Torsten Naucke, Gaetano Oliva, Domenico Otranto, Maria Grazia Pennisi, Barend L. Penzhorn, Martin Pfeffer, Xavier Roura, Angel Sainz, SungShik Shin, Laia Solano-Gallego, Reinhard K. Straubinger, Séverine Tasker, Rebecca Traub, Susan Little   +37 more
doaj   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

MFPD: A Multiple Fungal Pathogen Detection Pipeline Across Diverse Habitats

Advanced Science, EarlyView.
The MFPD pipeline integrates a comprehensive ITS reference database of fungal pathogens, optimized parameters, and algorithms tailored for both full‐length and subregion sequences that balance accuracy and computational efficiency; it enables high‐throughput, species‐level identification from amplicon sequencing data, supporting large‐scale ...
Yi Shen, Xinrun Yang, Jiabao Yu, Yaozhong Zhang, Tianjie Yang, Yang Gao, Xiaofang Wang, Alexandre Jousset, Waseem Raza, Fang‐Jie Zhao, Qirong Shen, Gaofei Jiang, Zhong Wei, Yangchun Xu   +13 more
wiley   +1 more source

Assisting the Learning of Clinical Reasoning by Veterinary Medical Learners with a Case Example

Veterinary Sciences
Effective clinical reasoning is essential for veterinary medical education, particularly in managing complex cases. This review explores strategies for learning clinical reasoning by veterinary medical learners, using a case example of mastitis to ...
Gustavo Ferlini Agne, Amanda (Mandi) Nicole Carr, Roy Neville Kirkwood, Kiro Risto Petrovski   +3 more
doaj   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source