Results 81 to 90 of about 101,786 (295)

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

News from the forest of Mondulkiri: additions to the mosquito fauna of Cambodia (Diptera: Culicidae)

Parasite
Following the ongoing inventory efforts conducted in Cambodia by the Medical and Veterinary Unit of the Institut Pasteur du Cambodge, and after intensive collection work in the eastern part of the country, we report 20 new mosquito species from Cambodia.
Maquart Pierre-Olivier, Suor Kimhuor, Vantaux Amélie, Doeurk Bros, Chhoy Kalyan, Heng Kimly, Sen Saoya, Chea Rina, Nov Kimsear, Keum Theary, Leng Sokkeang, Boyer Sébastien   +11 more
doaj   +1 more source

In Situ Profiling of Nanoscale Strains Uncovers Mechano‐Architectural Predictors of Aging and Osteoarthritis Emergence

Advanced Science, EarlyView.
In situ mechanical loading of osteoarthritis‐prone murine knee joints reveals that spatial alterations in subchondral plate microarchitecture precede cartilage loss and promote a shift from coordinated epiphyseal strain dissipation in healthy joints to focal subchondral strain concentration in osteoarthritis‐prone joints.
Aikta Sharma, Lucinda A. E. Evans, Lucie E. Bourne, Jishizhan Chen, Alissa L. Parmenter, Joseph Brunet, Kamel Madi, Sebastian Marussi, Andrew A. Pitsillides, Peter D. Lee, Katherine A. Staines   +10 more
wiley   +1 more source

Cannabis, One Health, and Veterinary Medicine: Cannabinoids’ Role in Public Health, Food Safety, and Translational Medicine

Rambam Maimonides Medical Journal, 2020
Public health is connected to cannabis with regard to food, animal feed (feed), and pharmaceuticals. Therefore, the use of phytocannabinoids should be examined from a One Health perspective.
Sivan Ritter, Lilach Zadik-Weiss, Osnat Almogi-Hazan, Reuven Or   +3 more
doaj   +1 more source

Immediate Growth Control in Response to Boiling Histotripsy is Prognostic for Intratumoral Immune Activation

Advanced Science, EarlyView.
Boiling Histrotripsy (BH), a mechanical form of focused ultrasound (FUS), allows for non‐invasive and non‐ionizing tissue destruction. Utilizing a BH treatment protocol that yielded bifurcating primary tumor growth responses, we found that immediate BH‐induced tumor growth control identifies tumors with acute reductions in antigen‐presenting cells (APC)
Lydia E. Kitelinger, Matthew R. DeWitt, Carly M. Van Wagoner, Claire A. Conarroe, Charles C. Funk, Aaron B. Streit, AeRyon Kim, Richard J. Price, Timothy N. J. Bullock   +8 more
wiley   +1 more source

Medical and Veterinary Entomology

, 2009
Medical and Veterinary Entomology, Second Edition, has been fully updated and revised to provide the latest information on developments in entomology relating to public health and veterinary importance. Each chapter is structured with the student in mind,
Mullen, Gary R., Durden, Lance A.
core  

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

THE IMPORTANCE OF THE VETERINARY MEDICAL IN THE INTEGRATED PREVENTIVE MONITORING

ENVIRONMENTAL SMOKE, 2018
The Integrated Preventive Monitoring began in 2002 with the initiative of the Public Ministry of the State of Bahia, and the Hydrographic Basin Committee of the São Francisco River. In Alagoas the Defense Center of Environment Public Ministry of the State coordinates the same. The representation of the Veterinarian in Integrated Preventive Surveillance
José Andreey Almeida Teles, Isaac Manoel Barros de Albuquerque, Thiago Augusto Pereira de Moraes, Francisco Feliciano da Silva Junior, Wellington Diniz Machado Filho, Gil Dutra Furtado, Aleudson dos Santos Silva   +6 more
openaire   +3 more sources

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

Emerging Insect-Borne Diseases of Agricultural, Medical and Veterinary Importance

, 2016
Current migrations, due to several causes, but mainly consequence of climate changes, are causing several problems in Southern Europe. Some migrations are evident and at‐ tract attention immediately; others are silent, but still important, like several ...
M. Nicoletti, K. Murugan, G. Benelli
semanticscholar   +1 more source