Results 91 to 100 of about 2,543,913 (259)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The UN must provide secure medical and humanitarian assistance in Ukraine [PDF]

open access: bronze, 2022
D P Southall   +4 more
openalex   +1 more source

F-1 Food Assistance Program State Summary - January 2017 [PDF]

open access: yes, 2017
The Food Assistance Monthly Participation Report (F-1) is a monthly summary of Food Assistance program participation, statewide and for each Iowa county. It contains data starting with July 2016.

core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

F-1 Food Assistance Program State Summary - April 2018 [PDF]

open access: yes, 2018
The Food Assistance Monthly Participation Report (F-1) is a monthly summary of Food Assistance program participation, statewide and for each Iowa county. It contains data starting with July 2016.

core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Medical Assistance Chatbot

open access: green, 2023
Pratik Subhash Kokate   +4 more
openalex   +1 more source

F-1 Food Assistance Program State Summary New Format, July 2016 [PDF]

open access: yes, 2017
The Food Assistance Monthly Participation Report (F-1) is a monthly summary of Food Assistance program participation, statewide and for each Iowa county. It contains data starting with July 2016.

core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Can Health Foreign Assistance Break the Medical Brain Drain ? [PDF]

open access: yes
This paper analyse the impact of health foreign assistance on physicians' brain drain. We use the database from Bhargava and Docquier (2008) to explain physicians' brain drain and health foreign assistance from 1995 to 2003 using a bilateral gravity ...
Yasser Moullan
core   +3 more sources

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