Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Factors That Influence Access to Medical Assistance in Dying Services: An Integrative Review. [PDF]
Hewitt J +3 more
europepmc +1 more source
Reckless Criminality in the Provision of Medical Care Assistance and Its Prevention: a Specialist's View [PDF]
Екатерина Сенокосова +1 more
openalex +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Views on medical assistance in dying and related arguments: a survey of doctors and nurses at a university hospital. [PDF]
Sigurbjörnsson S +2 more
europepmc +1 more source
Delay between the onset of symptoms of acute myocardial infarction and seeking medical assistance is influenced by left ventricular function at presentation. [PDF]
R. J. Trent +4 more
openalex +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
For, against, and beyond: healthcare professionals' positions on Medical Assistance in Dying in Spain. [PDF]
Parra Jounou I +2 more
europepmc +1 more source
Medical assistance to the population of Pskov during the German occupation (1941-1944) [PDF]
Tatiana Khrishkevich
openalex +1 more source

