Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
International Comparison of Underlying Disease Among Recipients of Medical Assistance in Dying.
Heidinger B +9 more
europepmc +1 more source
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu +5 more
wiley +1 more source
The Movement Toward Physician-Assisted Suicide: A Step in the Wrong Direction [PDF]
Norris, Patrick
core +1 more source
When medical assistance in dying is not a last resort option: survey of the Canadian public. [PDF]
Choi WJW +3 more
europepmc +1 more source
Sex Hormones Associate With Amyotrophic Lateral Sclerosis Risk and Survival
ABSTRACT Amyotrophic lateral sclerosis (ALS) risk differs by sex and age, implicating sex hormones as potential modifiers. This study examined plasma levels of biologically active sex hormones and their association with ALS odds and survival in cases (females n = 131, males n = 189) and controls (females n = 138, males n = 150) from the University of ...
Stephen A. Goutman +5 more
wiley +1 more source
Review of \u3cem\u3ePhysician-Assisted Suicide\u3c/em\u3e edited by Robert F. Weir [PDF]
Lysaught, M. Therese
core +1 more source
Mental illness segregation and truncated autonomy within medical assistance in dying legislative frameworks in Colombia and Canada. [PDF]
Bastidas-Bilbao H +3 more
europepmc +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Advance Requests for Medical Assistance in Dying in the International Context: Some Legal Issues for the Canadian Case. [PDF]
Espericueta L.
europepmc +1 more source

