Results 91 to 100 of about 7,093,683 (260)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Centerscope [PDF]

open access: yes, 1987
Centerscope, formerly Scope, was published by the Boston University Medical Center "to communicate the concern of the Medical Center for the development and maintenance of improved health care in contemporary society.
Bernstein, Daniel S.   +2 more
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Procura de serviço médico por mulheres climatéricas brasileiras

open access: yesRevista de Saúde Pública
OBJETIVO: Identificar as causas e os fatores relacionados à procura de serviço médico por mulheres climatéricas. MÉTODOS: Realizou-se estudo descritivo e exploratório de corte transversal, de base populacional. Selecionaram-se, por meio de amostragem por
Adriana Orcesi Pedro   +4 more
doaj  

Formation of an organizational framework for the medical and economic analysis of the resort [PDF]

open access: yesСаратовский научно-медицинский журнал, 2014
The aim of the article is to provide medical and economic analysis of the resort at the present stage and to identify ways to optimize. Material and methods: medical and statistical, analytical, medical and economic analysis, experimental. Results.
Kizeev M.V., Lugovoy V.E.
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Organization of medical care in adult population with non-production eye injuries. [PDF]

open access: yesСаратовский научно-медицинский журнал, 2014
Aim: justify the need for institutional arrangements for the provision of medical care to adults with non-productive eye injuries. Material and Methods: analytical, medical, statistical, and comparative analysis. Results.
Karimova D.Y.   +2 more
doaj  

Centerscope [PDF]

open access: yes, 1986
Centerscope, formerly Scope, was published by the Boston University Medical Center "to communicate the concern of the Medical Center for the development and maintenance of improved health care in contemporary society.
Washington, Donna
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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