Results 121 to 130 of about 7,093,683 (260)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

A meta-analysis of alveolar bone grafting using bone substitutes in cleft lip and palate patients

Tzu Chi Medical Journal
In individuals with cleft lip and palate (CLP), an alveolar bone graft (ABG) is carried out for alveolar cleft closure. Several sources for ABG include autologous bone, xenologous bone, and alloplastic substitutes.
Indri Lakhsmi Putri, Pascalis Fabian, Citrawati Dyah Kencono Wungu   +2 more
doaj   +1 more source

Price Indexes for Medical Care Goods and Services: An Overview of Measurement Issues [PDF]

We review in considerable detail the conceptual and measurement issues that underlie construction of medical care price indexes in the U.S., particularly the medical care consumer price indexes (MCPIs) and medical-related producer price indexes (MPPIs ...
David M. Cutler, Ernst R. Berndt, Joseph P. Newhouse, Richard G. Frank, Zvi Griliches   +4 more
core  

Academy Expands Medical Forensic Care and Response [PDF]

, 2019
The Alaska Comprehensive Forensic Training Academy, the first of its kind in the nation, trains nurses and health care providers to support victims of interpersonal violence in a trauma-informed manner and to preserve potential evidence and information ...
Casto, L. Diane, Trujillo, Angelia
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

La necesidad del método clínico y de su enseñanza: the clinical method

Revista Cubana de Medicina
El método clínico, como método de la profesión médica, constituye un tema polémico entre muchos facultativos en cuanto a su vigencia o necesidad. Con este artículo se pretende contribuir a la fundamentación del porqué es necesario un método para atender ...
Luis Alberto Corona Martínez, Mercedes Fonseca Hernández   +1 more
doaj  

Centerscope [PDF]

, 1984
Centerscope, formerly Scope, was published by the Boston University Medical Center "to communicate the concern of the Medical Center for the development and maintenance of improved health care in contemporary society.
Annas, George J., Stengel, Elizabeth Bell   +1 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Centerscope [PDF]

, 1981
Centerscope, formerly Scope, was published by the Boston University Medical Center "to communicate the concern of the Medical Center for the development and maintenance of improved health care in contemporary society.
Black, Paul H.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source