Results 81 to 90 of about 5,641,379 (300)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Raising standards in clinical research – The impact of the ECRIN data centre certification programme, 2011–2016

Contemporary Clinical Trials Communications, 2017
The nature and the purpose of the ECRIN Data Centre Certification Programme are summarised, and a very brief description is given of the underlying standards (129 in total, divided into 19 separate lists).
C. Ohmann, S. Canham, J. Demotes, G. Chêne, J. Lauritsen, H. Martins, R.V. Mendes, E.B. Nicolis, A. Svobodnik, F. Torres   +9 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Licensure and Certification Workgroup (2017); Other title: Final report; Other title: Special act 17-21 : establishing a working group to review the licensure and certification process for certain nonprofit community providers

, 2017
Title from cover.; "December 31, 2017."; Includes appendix "Facility licensure and certification as defined in Special Act 17-21" (24 pages ; 28 cm)
Connecticut. Licensure and Certification Workgroup,
core  

Patient Safety, Professionalization, and Reimbursement as Primary Drivers for National Medical Interpreter Certification in the United States

Translation and Interpreting : the International Journal of Translation and Interpreting Research, 2013
In a medical setting, interpretation by unskilled bilingual individuals can have serious repercussions when it results in a lower standard of care for minority-language patients.
Izabel S. Arocha, Linda Joyce
doaj  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Forest Certification: Toward Common Standards? [PDF]

The forestry industry provides a good illustration of the active roles that industry associations, environmental nongovernmental organizations (NGOs), national governments, and international organizations can play in developing and promoting codes of ...
Fischer, Carolyn, Sedjo, Roger, Aguilar , Francisco, Jawahar, Puja   +3 more
core  

Characteristics of family medicine physician associates/assistants in the United States

BMC Health Services Research
Background The family medicine (FM) workforce in the United States (U.S.) includes physicians, physician associates/assistants (PAs), and nurse practitioners (NPs).
Bethany Grubb, Cynthia F. Griffith, Mirela Bruza-Augatis, Kasey Puckett, Andrzej Kozikowski   +4 more
doaj   +1 more source

Continuing medical education in Turkey: Recent developments

BMC Medical Education, 2002
Background The Turkish Association of Medicine founded a Continuing Medical Education Accreditation Committee in 1993 to evaluate and accredit scientific meetings and publications.
Yaman Hakan
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source