Results 21 to 30 of about 422,411 (267)

Development of a Novel Wasp-Inspired Friction-Based Tissue Transportation Device

Frontiers in Bioengineering and Biotechnology, 2020
Currently existing tubular transportation systems for the extraction of large tissue masses during Minimal Invasive Surgery (MIS) are subjected to a large amount of operating limitations.
Aimée Sakes, Ivo A. van de Steeg, Esther P. de Kater, Perry Posthoorn, Marta Scali, Paul Breedveld   +5 more
doaj   +1 more source

Jain’s hand retractor system and stand: an innovative device for hand surgery

Archives of Plastic Surgery, 2021
Solo hand surgery is becoming increasingly common, mostly due to a lack of assistants and dedicated operating theatres. The solo hand surgeon faces challenges of proper hand positioning, elevation, and skin flap/tissue retraction.
Aakansh Jain
doaj   +1 more source

Nonclinical Bench Performance Testing of a Very Low-Cost Nonelectric Bubble Continuous Positive Airway Pressure (bCPAP) and Blenders Device Designed for Newborn Respiratory Support

Medical Devices: Evidence and Research, 2022
Patricia S Coffey, Alec Wollen Medical Devices and Health Technologies, PATH, Seattle, Washington, USACorrespondence: Patricia S Coffey, Medical Devices and Health Technologies, PATH, Seattle, WA, USA, Tel +1 206 285-3500, Fax +1 206 285-6619, Email ...
Coffey PS, Wollen A
doaj  

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka, Tsukuru Amano, Akimasa Takahashi, Mari Deguchi, Hiroyuki Yamanaka, Yuji Tanaka, Shunichiro Tsuji, Takashi Murakami   +7 more
wiley   +1 more source

Potential of magnetic shape memory alloys in medical applications

Current Directions in Biomedical Engineering
Systems based on smart materials have become an increasing research focus in recent years, as their properties provide opportunity for higher functional integration, improved energy efficiency and completely new functionalities.
Hutter Marco, Mayer Juliane, Schäfer Max B., Pott Peter P., Gundelsweiler Bernd   +4 more
doaj   +1 more source

Expanding Quality by Design Principles to Support 3D Printed Medical Device Development Following the Renewed Regulatory Framework in Europe

Biomedicines, 2022
The vast scope of 3D printing has ignited the production of tailored medical device (MD) development and catalyzed a paradigm shift in the health-care industry, particularly following the COVID pandemic.
Livia Adalbert, S P Yamini Kanti, Orsolya Jójárt-Laczkovich, Hussein Akel, Ildikó Csóka   +4 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Design, implementation, and management of an international medical device registry

Trials, 2021
Background Registries are powerful clinical investigational tools. Although in hospitals registries may be mandated, industry-sponsored, international registries are voluntary and therefore can require clearer objectives and more planning.
Herbert Mauch, Jasmin Kaur, Colin Irwin, Josie Wyss   +3 more
doaj   +1 more source

Impact of Design on Medical Device Safety [PDF]

Therapeutic Innovation & Regulatory Science, 2019
The growing number of emerging medical technologies and sophistication of modern medical devices (MDs) that improve both survival and quality of life indexes are often challenged by alarming cases of vigilance data cover-up and lack of sufficient pre- and post-authorization controls.
Miclăuş, Teodora, Valla, Vasiliki, Koukoura, Angeliki, Nielsen, Anne Ahlmann, Dahlerup, Benedicte, Tsianos, Georgios-Ioannis, Vassiliadis, Efstathios   +6 more
openaire   +2 more sources