EARLY SYMPTOMS AND DIAGNOSIS OF TUBERCULAR JOINT DISEASE.Read in the Section on Surgery and Anatomy at the Forty-fifth Annual Meeting of the American Medical Association, held at San Francisco, June 5-8, 1894. [PDF]
Emmet Rixford
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DRG prospective payment system: refine or not refine? [PDF]
We present a model of contracting between a purchaser of health services and a provider (a hospital). We assume that hospitals provide two alternative treatments for a given diagnosis: a less intensive one (for example a medical treatment) and a more ...
Elín J. G. Hafsteinsdóttir+1 more
core
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
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A CLINICAL TEXT-BOOK OF MEDICAL DIAGNOSIS for Physicians and Students, Based on the Most Recent Methods of Examination [PDF]
OSWALD VIERORDT, Francis H. Stuart
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Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
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THE GRAPHOPHONE IN MEDICINE: A NEW ADDITION TO MEDICAL ART IN DIAGNOSIS. [PDF]
Benjamin Ward Richardson
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This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
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An Address ON THE DIAGNOSIS AND TREATMENT OF SOME COMMON INFLAMMATORY AFFECTIONS OF THE EYE, FROM THE STANDPOINT OF THE GENERAL PRACTITIONER: Delivered before the Stratford Division of the British Medical Association [PDF]
Erin Henderson
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This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci+6 more
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The Medical Check-up or Pre-symptomatic Diagnosis [Abridged] [PDF]
R. R. Bomford
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