Results 161 to 170 of about 10,069,788 (309)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Medical College Hospital, May 1953

, 1953
This glass lantern slide features an aerial view of the Medical College of South Carolina Hospital under construction in May ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Medical Center construction, Roper Hospital, Pinehaven Sanatorium, November 1953

, 1953
This glass lantern slide features a ground view of the construction of the Medical College of South Carolina Medical Center, at left, Roper Hospital, and Pinehaven Sanatorium in November ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

Retrieval Augmented Medical Diagnosis System. [PDF]

Biol Methods Protoc
Johnson ET, Bande JK, Thomas J.
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Machine learning driven biomarker selection for medical diagnosis. [PDF]

PLoS One
Bavikadi D, Agarwal A, Ganta S, Chung Y, Song L, Qiu J, Shakarian P.   +6 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Medical College Hospital, April 3, 1955

, 1955
This glass lantern slide features a ground view of the Medical College of South Carolina Hospital in April of ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

A Review of Machine Learning-Assisted Gas Sensor Arrays in Medical Diagnosis. [PDF]

Biosensors (Basel)
Yu Y, Cao X, Li C, Zhou M, Liu T, Liu J, Zhang L.   +6 more
europepmc   +1 more source