Results 121 to 130 of about 13,249,415 (385)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Incorporating Environmental Health into Pediatric Medical and Nursing Education [PDF]

, 2004
Pediatric medical and nursing education currently lacks the environmental health content necessary to appropriately prepare pediatric health care professionals to prevent, recognize, manage, and treat environmental-exposure–related disease.
Allen Dearry, Bonnie Rogers, James Roberts, Jerome Paulson, Leyla Erk McCurdy, Lindberg MA, Nsedu Obot Witherspoon, Rebecca Love, Rogers B, Rogers B, Rogers B, Ruth Etzel   +11 more
core   +3 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Teaching and Learning with Videoconferencing at Regional Medical Campuses

Journal of Regional Medical Campuses, 2019
Distributed medical education, and instruction at regional medical campuses, is becoming more prevalent. With its focus on connecting learners in multiple environments outside of traditional classroom or clinical environments, the role of technology is ...
Anna MacLeod, Paula Cameron, Olga Kits, Gregory Power, Jonathan Tummons   +4 more
doaj   +1 more source

Research knowledge and skills in primary medical training: A crosssectional audit [PDF]

, 2016
This article was migrated. The article was marked as recommended. Background: Internationally, medical education has either adopted, or is moving toward, a Masters level qualification at completion.
Allen, Penny, Cheek, Colleen, Hays, Richard, Smith, Janie Dade   +3 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Concepções do processo ensino-aprendizagem: um estudo com professores de medicina

Revista Brasileira de Educação Médica
Este artigo aborda a docência médica como um processo de construção social, que articula condicionantes político-acadêmicos, pedagógicos, pessoais e intersubjetivos.
Angela Maria Moreira Canuto, Sylvia Helena Souza da Silva Batista   +1 more
doaj   +1 more source

Curated Collections for Educators: Eight Key Papers about Feedback in Medical Education [PDF]

, 2019
Feedback is an essential part of learning, growth, and academic success. Junior faculty members are often unfamiliar with the grounding literature that defines feedback.
Gottlieb, Michael, Krzyzaniak, Sara M., Natesan, Sreeja M., Shaw, Rebecca, Stehman, Christine, Story, David   +5 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Pesquisa em educação médica conduzida por estudantes: um ano de experiência do núcleo acadêmico de pesquisa em educação Médica

Revista Brasileira de Educação Médica
A pesquisa em educação médica vem se desenvolvendo muito nos últimos anos. A participação de estudantes nos processos de mudanças curriculares também é crescente e bastante contributiva.
Pedro Tadao Hamamoto Filho, Vinicius Cunha Venditti, Licério Miguel, Ludmila Almeida Silva, Cristiano Claudino Oliveira, José Carlos Peraçoli   +5 more
doaj   +1 more source