Results 91 to 100 of about 2,008,711 (315)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Relationship between Occupational Stress and Mental Health in Male Personnel of Medical Emergency in Golestan Province

open access: yesJournal of Research Development in Nursing and Midwifery, 2015
Background and Objective: One of the environmental factors bringing about chronic stress is something that is related to occupation. Because mental health improvement of a society particularly in a productive group is a necessity for dynamics and ...
Zahra Moshtagh Eshgh   +4 more
doaj  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Pneumothorax and Pneumomediastinum in a Sputum Positive Tuberculosis Patient: The Continuous Diaphragm Sign [PDF]

open access: yes, 2012
Secondary pneumothorax is a very common medical emergency. At times it is associated with pneumomediastinum, which could be fatal at times if not identified.
Bhatia, V   +5 more
core   +1 more source

Nurse led care [PDF]

open access: yes, 2005
What's the difference between medical and nursing care? The answer is not straightforward, but shortages in the medical workforce mean that nurses are increasingly called on to undertake work that was previously done by doctors (such as undertaking ...
Cullum, N, Richardson, G, Spilsbury, K
core   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Are You Applying to More Than One Specialty? [PDF]

open access: yes, 2019
Although the majority of U.S. medical students predominantly apply to only one specialty, some apply to more than one. When it comes to emergency medicine (EM), applicants may apply to additional specialties due to several reasons: being international ...
Cheaito, Mohamad Ali   +8 more
core   +2 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

The state of attitude towards safety in pre-hospital emergency personnel of Ardabil province in 2023 [PDF]

open access: yesSalāmat-i kār-i Īrān
Background and aims: Patient safety is one of the basic indicators of health care, and investigating patient safety culture is a movement towards providing safe conditions for patient care.
saeid mehri   +3 more
doaj  

Medical Emergencies in Dental Practice - A Nepalese study

open access: yesOrthodontic Journal of Nepal, 2015
Introduction: Medical emergencies can occur in dental practice anytime. Changing demographics in the population and increased life expectancy have resulted in more people having medical conditions which predispose to a medical emergency.
Sandhya Joshi, Sudeep Acharya
doaj   +1 more source

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