Results 91 to 100 of about 6,513,119 (298)

Construction of health monitoring system for traveler based on the mobile Internet

open access: yes上海师范大学学报. 自然科学版, 2017
With the development of communication technology and computer technology,intelligent terminals represented by smartphone and mobile Internet have become indispensable tools in people's life and work.As the intelligent terminal platform is widely used and
Wei Haoqian, Yin Ye, Tang Wei, Peng Ye
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Iran’s policies aimed at supporting medical equipment development during the COVID-19 [PDF]

open access: yesبهبود مدیریت
In recent years, the occurrence of unexpected events such as climate change, environmental destruction, and health pandemics, in addition to creating social, economic, and political disturbances, highlights the strengthening of the infrastructure to deal
Kiarash Fartash   +3 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Women's participation in health care development in Dagestan in the 1960s: history, problems

open access: yesВестник Майкопского государственного технологического университета
Satisfaction of the increased demands of medical institutions for trained doctors and secondary medical workers, ensuring gender equality in this socially significant matter, especially in its Muslim regions are considered to be the most important ...
M. Ya. Mirzabekov
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

The Role of Weak Ties in Diversification Strategy

open access: yesAnnals of Business Administrative Science, 2016
This study provides an analysis of the successful diversification process from the perspective of “weak ties.” Weak ties bring about new knowledge that does not overlap existing knowledge and are therefore useful to firms entering new markets. This study
Hideko KONO
doaj   +1 more source

3D printing for development of medical equipment amidst coronavirus (COVID-19) pandemic—review and advancements

open access: yesResearch on Biomedical Engineering, 2020
Background and aims Coronavirus (COVID-19) has surfaced as a global pandemic and has created an unprecedented global demand for medical equipment. The shortage of onsite workforce, need for social distancing and less time available for sourcing have ...
Mir Irfan Ul Haq   +6 more
semanticscholar   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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