Results 51 to 60 of about 1,727,171 (292)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Medical equipment for expeditions. [PDF]

open access: yesBMJ, 1981
Each year more than 200 expeditions leave Britain to travel to destinations around the world, to climb mountains, explore jungles, to study plants or beetles, and to seek excitement and adventure. Expeditions may differ greatly in size, duration, objectives, and activities, but none can avoid the possibility of accident or illness.
openaire   +3 more sources

Compression and R-wave detection of ECG/VCG data [PDF]

open access: yes, 1972
Application of information theory to eliminate redundant part of electrocardiogram or vectorcardiogram is described. Operation of medical equipment to obtain three dimensional study of patient is discussed.
Bennett, W. P.   +2 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Extraction and Analysis of Respiratory Motion Using Wearable Inertial Sensor System during Trunk Motion

open access: yesSensors, 2017
Respiratory activity is an essential vital sign of life that can indicate changes in typical breathing patterns and irregular body functions such as asthma and panic attacks.
Apoorva Gaidhani   +4 more
doaj   +1 more source

A preliminary audit of medical and aid provision in English Rugby union clubs:compliance with Regulation 9 [PDF]

open access: yes, 2018
BackgroundGoverning bodies are largely responsible for the monitoring and management of risks associated with a safe playing environment, yet adherence to regulations is currently unknown. The aim of this study was to investigate and evaluate the current
A Ackery   +21 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Sairaanhoitajien kokemuksia lääkintälaitteiden käytöstä Lohjan sairaalan päivystyspoliklinikalla [PDF]

open access: yes, 2016
Opinnäytetyön tarkoituksena oli selvittää sairaanhoitajien kokemuksia lääkintälaitteiden käytöstä. Tarkoituksena oli myös kartoittaa käytön esteitä ja edistäviä tekijöitä sairaanhoitajien kokemuksien kautta.
Grip, Jukka
core  

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