Results 51 to 60 of about 1,735,295 (293)

Representations of medical instruments and equipment in Serbian medieval painting [PDF]

open access: yesZograf, 2014
The paper topic is identification of medical instruments and equipment using the images preserved in Serbian medieval painting. This topic has not been the subject of special study in the Serbian science.
Pajić Sanja
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Medical equipment for expeditions. [PDF]

open access: yesBMJ, 1981
Each year more than 200 expeditions leave Britain to travel to destinations around the world, to climb mountains, explore jungles, to study plants or beetles, and to seek excitement and adventure. Expeditions may differ greatly in size, duration, objectives, and activities, but none can avoid the possibility of accident or illness.
openaire   +3 more sources

Systemwide Clinical Ultrasound Program Development: An Expert Consensus Model. [PDF]

open access: yes, 2018
Clinical ultrasound (CUS) is integral to the practice of an increasing number of medical specialties. Guidelines are needed to ensure effective CUS utilization across health systems.
Abo, Alyssa   +19 more
core   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Extraction and Analysis of Respiratory Motion Using Wearable Inertial Sensor System during Trunk Motion

open access: yesSensors, 2017
Respiratory activity is an essential vital sign of life that can indicate changes in typical breathing patterns and irregular body functions such as asthma and panic attacks.
Apoorva Gaidhani   +4 more
doaj   +1 more source

The Brazilian experience in design for health: Interdisciplinary and Bioethics [PDF]

open access: yes, 2009
Health design in Brazil has been characterized historically by replacing imported products with others that are locally manufactured on a small scale. The formation of interdisciplinary groups has never been submitted to specific norms, particularly at ...
Bonatti, Fernanda Alves da Silva   +2 more
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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