Results 131 to 140 of about 1,825,467 (355)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Orbit Error Correction on the High Energy Beam Transport Line at the KHIMA Accelerator System

open access: yes, 2016
For the purpose of treatment of various cancer and medical research, the synchrotron based medical machine under the Korea Heavy Ion Medical Accelerator (KHIMA) project have been conducted and is going to treat the patient at the beginning of 2018.
An, Dong Hyun   +3 more
core   +1 more source

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga   +8 more
wiley   +1 more source

Patient safety in the undergraduate curriculum: Medical students' perception [PDF]

open access: yes, 2010
Objective Patient safety has emerged as a distinct health care discipline and an undergraduate programme on patient safety is being introduced at the authors' institution.
Leung, GKK, Patil, NG
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Partially Identifying the Prevalence of Health Insurance Given Contaminated Sampling Response Error [PDF]

open access: yes
This paper derives simple closed-form identification regions for the U.S. nonelderly population's prevalence of health insurance coverage in the presence of household reporting errors.
Kreider, Brent
core  

Implementation of a Standardized Handoff System for a General Surgery Residency Program [PDF]

open access: yes, 2017
Introduction: The I-PASS Handoff Bundle is an evidence based standardized set of educational materials designed to decrease handoff failures in patient care. Two of every three sentinel events , the most serious events reported to the Joint Commission,
Brown, A. M.   +6 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy