Results 131 to 140 of about 889,273 (265)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Medical Errors - The Third Killer?

open access: yesAnnals of Abbasi Shaheed Hospital and Karachi Medical & Dental College, 2017
Faisal Alnasir
doaj   +1 more source

Assessment of medical errors awareness among nursing students during their clinical internship: Palestinian perspectives. [PDF]

open access: yesBMC Med Educ
Salameh B   +9 more
europepmc   +1 more source

Experimental evidence for structured information-sharing networks reducing medical errors. [PDF]

open access: yesProc Natl Acad Sci U S A, 2023
Centola D   +5 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Pantethine therapy dramatically rescues end‐stage failing heart in a patient with deficiency of coenzyme A biosynthesis

open access: yesESC Heart Failure
Violette Goetz   +9 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Global Trends and Evidence Gaps in Medical Errors Research: A Mixed-Methods Scientometrics Study. [PDF]

open access: yesJ Multidiscip Healthc
Angarita-Pacheco Y   +8 more
europepmc   +1 more source

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