Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Learning From Mistakes: Navigating Medical Errors in Oncology From Prevention to Management. [PDF]
Karp DD, Osburn JA, Gouda MA.
europepmc +1 more source
An urban medical system's exploratory study of medication errors [PDF]
Skip Morelock, Jeffrey D. Kirk
openalex +1 more source
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst +4 more
wiley +1 more source
Bayesian Tragedy and Categorical Medical Error in Prostate Cancer [PDF]
Nery Lamothe +3 more
openalex +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Self-Reported Medical Errors and Primary Care Physicians' Performance and Confidence in Delivering Care: A Multilevel Empirical Study in China. [PDF]
Sun X, Zhou Z, Wang W.
europepmc +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Exploring the impact of interaction dynamics and professional capacity and development on cognitive medical errors: a multiple-case study of healthcare professionals in Jordan. [PDF]
Hijazi H +7 more
europepmc +1 more source
IryoNLP at MEDIQA-CORR 2024: Tackling the Medical Error Detection & Correction Task On the Shoulders of Medical Agents [PDF]
Jean-Philippe Corbeil
openalex +1 more source

