Results 161 to 170 of about 7,494,393 (373)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Deep Ecology and End-of-Life Care

, 2009
Physicians and nurses caring for terminally ill patients are expected to center their moral concerns almost exclusively on the needs and welfare of the dying patient and the patients family.
Carrick, Paul
core  

New horizons in medical ethics. Who is the patient's friend? [PDF]

, 1973
R. Klein, David A. Pyke, Anthony M. Smith   +2 more
openalex   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Ethics support for ethics support: the development of the Confidentiality Compass for dealing with moral challenges concerning (breaching) confidentiality in moral case deliberation

BMC Medical Ethics
Background Confidentiality is one of the central preconditions for clinical ethics support (CES). CES cases which generate moral questions for CES staff concerning (breaching) confidentiality of what has been discussed during CES can cause moral ...
Wieke Ligtenberg, Margreet Stolper, Bert Molewijk   +2 more
doaj   +1 more source

Information about wanted persons and medical ethics [PDF]

, 1979
MK Thomas
openalex   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Progress in Medical Ethics: How the Ethicist Can Help [PDF]

, 1976
In this article Dr. Camenisch presents a plea for mutual understanding between ethicists and medical professionals. He is Associate Professor of Religious Studies at DePaul University and is a post-doctoral Fellow at the Texas Institute of ...
Camenisch, Paul F.
core   +2 more sources

Methodology of teaching and evaluation of medical ethics course from the perspective of teachers

آموزش پزشکی, 2017
BACKGROUND AND OBJECTIVE: Medical ethics is one of the lessons which were added to general medical curriculum in recent years. Experimental nature of this course requires having its own training and assessment methods.
SeyedEsmaeil Managheb, Yahya Sadeghi-Mazidi   +1 more
doaj  

MEDICAL ETHICS

, 1928
FRED C. ZAPFFE
openalex   +1 more source