Results 41 to 50 of about 3,479,193 (278)

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges   +12 more
wiley   +1 more source

Ethical approval in developing countries is not optional [PDF]

open access: yes, 2012
When conducting health and medical research it is not only important to do the research ethically, but also to apply for prior ethical approval from the relevant authorities.
Simkhada, Padam, van Teijlingen, Edwin
core   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine   +14 more
wiley   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Virtue and care ethics & humanism in medical education: a scoping review

open access: yesBMC Medical Education, 2022
Purpose This scoping review explores how virtue and care ethics are incorporated into health professions education and how these factors may relate to the development of humanistic patient care.
David J. Doukas   +5 more
doaj   +1 more source

Practicing Sport in the Age Group 21-34 and the Risk of Breast Cancer - Analysis of the Results of a Retrospective Study

open access: yesCentral European Journal of Sport Sciences and Medicine, 2023
Breast cancer is the most common malignant tumor in women, so it is important to study the factors that can protect against it. One of them is physical activity, which has become the area of our interest, especially the practice of sports by women aged ...
Aleksandra Kładna   +5 more
doaj   +1 more source

Protocol for a systematic scoping review of reasons given to justify the performance of randomised controlled trials. [PDF]

open access: yes, 2019
IntroductionRandomised controlled trials (RCTs) are widely viewed to generate the most reliable medical knowledge. However, RCTs are not always scientifically necessary and therefore not always ethical.
Chevrier, Stephanie   +7 more
core   +2 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

PROMOTING GLOBAL HEALTH: THE WORLD ASSOCIATION OF MEDICAL EDITORS POSITION ON EDITORS’ RESPONSIBILITY

open access: yesKhyber Medical University Journal, 2015
We live in a world community. Our countries are interconnected in ways unanticipated by previous generations. This new reality means that global health can only be achieved through collaboration, cooperation, and sharing of resources across boundaries ...
Lorraine E Ferris   +2 more
doaj  

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

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