Results 111 to 120 of about 10,895,625 (310)

A Versatile DNA‐Encoded Library Platform for the Discovery of Highly Cooperative Chemical Inducers of Proximity

open access: yesAdvanced Science, EarlyView.
We present a versatile DNA‐encoded library (DEL) platform designed for rapid library synthesis and subsequent screening for chemical inducers of proximity (CIPs) across various presenter proteins of choice. Applying this approach, we discovered a novel molecular glue‐like compound mediating CRBN‐BRD9 ternary complex formation with remarkable ...
Bingqi Tong   +11 more
wiley   +1 more source

South African collective investment scheme performance fees [PDF]

open access: yes, 2014
Includes bibliographical references.This paper is an analysis of the South African Collective Investment Schemes (CIS) performance fee structure. The paper looks at the methods used in the calculation of performance fees and provides a detailed breakdown
Haldane, Andrew
core   +1 more source

Long-term trends in international medical electives fees: a database mining study

open access: yesBMC Medical Education
Background Abroad medical electives are recognized as high-impact practice and considered a necessity to provide global health training. As of recently, the COVID-19 pandemic and its related travel restrictions prohibited most international elective ...
Kai Beckschulte   +2 more
doaj   +1 more source

Nascent Extracellular Matrix Converts Biomaterial Cues into Cell Fate Decisions

open access: yesAdvanced Science, EarlyView.
This study uncovers a tri‐directional interplay among cells, hydrogels, and their nascent extracellular matrix. Hydrogel norbornene modification alters CD44‐mediated cell–hydrogel interactions, which shape nascent matrix deposition, composition, and spatial organization.
Joshua Y. Liu   +12 more
wiley   +1 more source

Manifesto for medical research [PDF]

open access: yes, 2015
The MRCG want to ensure there is a dynamic medical research environment in Ireland. Ensuring priority investment for medical research will help to deliver patient care, public health service transformation and economic and enterprise development.
Medical Research Charities Group
core  

Acoustically Activatable Drug‐Loaded Nanodroplets for Mechanochemical Therapy in Solid Tumors

open access: yesAdvanced Science, EarlyView.
Microfluidically fabricated drug‐loaded nanodroplets are sequentially activated by dual‐frequency ultrasound through acoustic droplet vaporization followed by bubble collapse, enabling spatially controlled drug release and mechanical tumor fractionation, resulting in synergistic mechanochemotherapy and prolonged survival.
Tiran Bercovici   +4 more
wiley   +1 more source

Remuneração do trabalho médico: um estudo sobre seus sistemas e formas em hospitais gerais de Belo Horizonte

open access: yesCadernos de Saúde Pública
Com o propósito de realizar uma análise descritiva dos sistemas e formas de remuneração do trabalho médico em hospitais gerais de Belo Horizonte e apreender a percepção de gerentes hospitalares, médicos e representantes das associações corporativas ...
Mariangela L. Cherchiglia
doaj  

A Generalizable Multimodal Model for Treatment‐Stratified Risk and Survival Assessment under Real‐World Constraints: A Multi‐Center Study of Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
DAIMS is a multimodal model for treatment stratified risk and survival assessment in colorectal cancer. Training draws on pathology, genomics, and clinical reports, yet inference requires only whole slide images, and adaptation to new cohorts proceeds without target survival outcomes.
Chuangjie Cao   +15 more
wiley   +1 more source

An epidemiological investigation of the prevalence of digestive diseases in the older prisoner population in Taiwan

open access: yesJournal of Health, Population and Nutrition
Objective The prison population has been increasing globally, and prisoner health is an important issue of global health. However, it has not received sufficient attention, especially in developing countries and regions.
Zhu Liduzi Jiesisibieke   +4 more
doaj   +1 more source

Consumer Price Index Changes in Iran\'s Public and Health Sectors [PDF]

open access: yesپژوهشهای اقتصادی, 2010
One of the major macroeconomic objectives of the governments is to control the inflation rate. High inflation and its associate destructive impacts on public welfare are concerned by social and economic policymakers. Consequently, they aim to control the
Ali Mohammad Ahmadi   +2 more
doaj  

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