Results 211 to 220 of about 10,895,625 (310)
Sustained Inhibition of Structural Damage Progression and Improvements in Disease Activity With Guselkumab in Biologic‐Naïve Participants with Active and Erosive Psoriatic Arthritis: Results Through Week 48 of the Phase 3b Randomized, Double‐Blind, Placebo‐Controlled APEX Study
Arthritis &Rheumatology, Accepted Article.Objective
In APEX, guselkumab, which binds to the IL‐23p19 subunit and CD64 on IL‐23‐producing cells, demonstrated significant joint efficacy and inhibition of structural damage progression in participants with active and erosive PsA through Week (W)24; W48 findings are reported herein. Methods
The APEX modified full analysis set included 1020 biologic‐Christopher T. Ritchlin, Philip J. Mease, Laura C. Coates, Alexa P. Kollmeier, Bei Zhou, Yusang Jiang, Karen Bensley, Koeun Im, Rattandeep Batra, Karissa Lozenski, Soumya D. Chakravarty, Proton Rahman, Désirée van der Heijde +12 morewiley +1 more sourceEffectiveness of oral anticoagulants in precapillary pulmonary hypertension associated with systemic sclerosis: a EUSTAR cohort study. [PDF]
Rheumatology (Oxford)Farina N, Bellando Randone S, Jenssen-Bjørkekjær H, Sanges S, Carreira P, Airò P, Guiducci S, Giuggioli D, Riemekasten G, Simeón Aznar CP, Bergmann C, Siegert E, Castellví I, Saketkoo LA, de Vries-Bouwstra J, Klemm P, Müller-Ladner U, Balbir-Gurman A, Smith V, Iannone F, Idolazzi L, Denton C, Rosato E, Maurer B, Allanore Y, Tanaka Y, Zanatta E, Truchetet ME, Kuwana M, Martin M, Cauli A, Solanki K, Del Galdo F, Gheorghiu AM, Anic B, Boleto G, Kumánovics G, Andréasson K, Rednic S, Chung LS, Oliveira S, Cadar M, Corrado A, de Souza Müller C, Hsu VM, Levy Y, Moroncini G, Henes J, Balanescu A, De Langhe E, Montecucco C, Sfikakis PP, Iudici M, Heitmann S, Vonk MC, Hoffmann-Vold AM, Distler O, Matucci Cerinic M, Bruni C. +58 moreeuropepmc +1 more sourceThe development and validation of a new diagnostic sonographic enthesitis score for psoriatic arthritis: Diagnostic Ultrasound Enthesitis Tool (DUET)
Arthritis &Rheumatology, Accepted Article.Objective
The Diagnostic Ultrasound Enthesitis Tool (DUET) study aimed to develop and validate a new sonographic scoring system for enthesitis to aid PsA diagnosis. Methods
We prospectively enrolled patients with early PsA, psoriasis without arthritis (PsO), and non‐inflammatory musculoskeletal symptoms as controls (CTL) from 17 centers. A standardized Lihi Eder, Andre L. Ribeiro, Ricardo Acayaba de Toledo, Catherine Bakewell, Philippe Carron, Basant Elnady, Amir Haddad, Arthur Kavanaugh, Arnon Katz, Minna J. Kohler, Josefina Marin, Fahmeen Afgani, Nikolas Malliotis, Nam Nguyen, Adrien Nzeusseu, Ari Polachek, Ernesto Rodriguez, Marcos Rosemffet, Abha Singh, Maria S. Stoenoiu, Agnes Szentpetery, Ilaria Tinazzi, Janeth Yinh, Mu Yang, Dennis McGonagle, Richard Cook, Gurjit S. Kaeley, Sibel Z. Aydin +27 morewiley +1 more sourceEfficacy and biomarker analysis for nivolumab in cancer of unknown primary: results from an investigator-initiated expanded access program. [PDF]
Int J Clin OncolTanizaki J, Yonemori K, Takiguchi Y, Akiyoshi K, Komine K, Onozawa Y, Sato M, Hirata K, Onoe T, Ohkuma R, Horita Y, Minami H, Honda K, Suyama K, Ito A, Chiba Y, Watanabe H, Togashi Y, Sakai K, Nishio K, Nakagawa K, Hayashi H. +21 moreeuropepmc +1 more sourceDifferentiation and Pathological Significance of Tissue‐Resident Memory‐Like CD8+ T Cells in Systemic Lupus Erythematosus
Arthritis &Rheumatology, Accepted Article.Objective
Tissue‐resident memory T (TRM) cells have been implicated in organ‐specific immune pathology; however, the pathological relevance of TRM‐like CD8+ T cells in systemic lupus erythematosus (SLE) remains unclear. We investigated their differentiation mechanisms and pathological significance in SLE, including associations with disease activity ...Yuya Fujita, Kaoru Yamagata, Satoshi Kubo, Ippei Miyagawa, Koshiro Sonomoto, Yurie Satoh‐Kanda, Masanobu Ueno, Shumpei Kosaka, Aya Nawata, Yoshiya Tanaka, Shingo Nakayamada +10 morewiley +1 more sourceMedical Center grounds diagram
This glass lantern slide features a black and white diagram of the Medical College of South Carolina Medical Center ...Medical College of South Carolina (1952-1969). Department of Medical Illustrationcore Legal and ethical considerations around the use of existing illustrations to generate new illustrations in the anatomical sciences
Anatomical Sciences Education, Volume 18, Issue 3, Page 289-300, March 2025.Abstract
It is likely existing anatomical illustrations are often used as the basis for new illustrative works, given not all illustrators have access to human tissues, bodies, or prosections on which to base their illustrations. Potential issues arise with this practice in the realms of copyright infringement and plagiarism when authors are seeking to Jon Cornwall, Richard White, Patrick Pennefather, Sabine Hildebrandt, Jill Gregory, Heather F. Smith, Jason Organ, Claudia Krebs +7 morewiley +1 more sourceImproved outcomes with TKI maintenance after brexucabtagene autoleucel in Philadelphia chromosome ALL. [PDF]
Blood AdvOthman T, Roloff GW, Miller K, Zhang A, Sutherland KC, Faramand R, Hill LC, Muhsen IN, Jeyakumar N, Ladha A, Sasine J, Lin C, Kopmar NE, Tsai SB, O'Connor TE, Hilal T, Solh MM, Guzowski C, Tan V, Majhail NS, Battiwalla M, Malik S, Mathews J, Shaughnessy P, Mountjoy L, Dykes KC, Logan AC, Schwartz M, Connor MP, Wang J, Vasu S, Kumaran M, Hoeg R, Tracy SI, Yalniz F, Yaghmour G, Pullarkat V, Cassaday RD, Leonard JT, Shah BD, Frey NV, Muffly LS, Aldoss I. +42 moreeuropepmc +1 more sourceClinical characteristics and severity classification in mixed connective tissue disease: a nationwide retrospective study. [PDF]
Rheumatology (Oxford)Kubo S, Kanda Y, Kameda H, Kuwana M, Narazaki H, Fujii T, Fujio K, Muro Y, Akamatsu K, Ohmura K, Ogura T, Shirai Y, Tanabe Y, Nakashima R, Tsuchida Y, Nakayamada S, Hasegawa H, Hirata S, Fukaya S, Kato T, Yasuoka H, Yamashita Y, Kono M, Atsumi T, Tanaka Y. +24 moreeuropepmc +1 more source