Results 41 to 50 of about 802,581 (339)

Nintedanib for systemic sclerosis–associated interstitial lung disease [PDF]

open access: yes, 2019
BackgroundInterstitial lung disease (ILD) is a common manifestation of systemic sclerosis and a leading cause of systemic sclerosis-related death. Nintedanib, a tyrosine kinase inhibitor, has been shown to have antifibrotic and antiinflammatory effects ...
Alves, Margarida   +16 more
core   +3 more sources

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Tarifas mínimas en cirugía general Minimal tariffs in surgery

open access: yesRevista Colombiana de Cirugía, 2006
Introducción: En el presente trabajo se cuestionan cuáles deben ser las tarifas mínimas (honorarios quirúrgicos) para los procedimientos en cirugía general.
Pablo García Echeverri
doaj  

Outcomes after angiography with sodium bicarbonate and acetylcysteine [PDF]

open access: yes, 2018
Background: Intravenous sodium bicarbonate and oral acetylcysteine are widely used to prevent acute kidney injury and associated adverse outcomes after angiography without definitive evidence of their efficacy.
,   +19 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Do Tuition Fees Affect the Mobility of University Applicants?: Evidence from a Natural Experiment [PDF]

open access: yes
Several German states recently introduced tuition fees for university education. We investigate whether these tuition fees influence the mobility of university applicants.
Johanna Storck   +2 more
core   +3 more sources

Parental perspectives on surgical fees of pediatric squint surgeries

open access: yesJournal of Clinical Ophthalmology and Research, 2014
Aim: To report the parental feedback on the ′squint surgery fees′ of their ward in an urban private practice. Design: Prospective cohort study. Subjects and Methods: Three months after the surgery, a 10 item questionnaire was administered on the parents ...
Mihir Kothari, Sheetal Baldua
doaj   +1 more source

Integrated Information System Smart E:Hospital the Innovation and Improvement of the Services and Management Hospital

open access: yesLontar Komputer, 2023
The use of technology can transform conventional systems into electronic-based systems. Electronic systems have been widely used in governance, organizations, and companies where administration is carried out electronically (e-Government).
Oka Sudana   +3 more
doaj   +1 more source

The human resource implications of improving financial risk protection for mothers and newborns in Zimbabwe [PDF]

open access: yes, 2013
Peer reviewedPublisher ...
A Chikanda   +45 more
core   +4 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

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