Results 171 to 180 of about 4,953,128 (334)

Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics

Genetics in Medicine, 2016
Sarah S. Kalia, Kathy Adelman, Sherri Bale, Wendy K Chung, Christine M. Eng, James P. Evans, Gail E. Herman, Sophia B. Hufnagel, Teri E Klein, Bruce R. Korf, Kent D. McKelvey, K. Ormond, C. Sue Richards, C. Vlangos, Michael S. Watson, Christa L. Martin, David T. Miller   +16 more
semanticscholar   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Telemedicine - chances and challenges for medical genetics in Germany. [PDF]

Med Genet, 2021
Tecklenburg J.
europepmc   +1 more source

Abstracts of the joint meeting of the Clinical Genetics Society and the Clinical Molecular Genetics Society held on 19 and 20 April 1990 at University of Newcastle upon Tyne Medical School [PDF]

, 1990
Mary Porteous, John Burn, S Proctort, C. Geoffrey Woods, Sarah Bundey, A. Malcolm R. Taylor   +5 more
openalex   +1 more source

ADDENDUM: Genetic counseling and testing for Alzheimer disease: joint practice guidelines of the American College of Medical Genetics and the National Society of Genetic Counselors

Genetics in Medicine, 2019
J. Goldman, S. Hahn, J. W. Catania, S. Larusse-Eckert, M. Butson, Malia C. Rumbaugh, M. Strecker, J. Roberts, W. Burke, R. Mayeux, T. Bird   +10 more
semanticscholar   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Basic concepts of medical genetics formal genetics, Part 3

Egyptian Journal of Medical Human Genetics, 2014
Mohammad Saad Zaghloul Salem
doaj   +1 more source

European training requirements for the specialty of medical genetics. [PDF]

Eur J Hum Genet
Moog U, Berg J, Kerr S, Turnpenny PD, Verloes A, Working Group ETR for Medical Genetics, Zschocke J.   +6 more
europepmc   +1 more source

Ethnicity-based classifications and medical genetics: One Health approaches from a Western Pacific perspective. [PDF]

Front Genet, 2022
Edinur HA, Mat-Ghani SNA, Chambers GK.
europepmc   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source