Results 181 to 190 of about 1,221,619 (355)
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Ethnicity-based classifications and medical genetics: One Health approaches from a Western Pacific perspective. [PDF]
Front Genet, 2022 Edinur HA, Mat-Ghani SNA, Chambers GK.
europepmc +1 more source
Recombinant DNA and Medical Genetics. Edited by Anne Messer and Ian Porter. Florida: Academic Press. 1983. 224 pp. £22.00 $33.00. ISBN 0 12 49222. [PDF]
, 1985 Nick Hastie
openalex +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Impact of the COVID-19 pandemic on medical genetics and genomics training: Perspective from clinical trainees. [PDF]
Am J Med Genet A, 2022 Chenbhanich J, Slavotinek A, Tam A.
europepmc +1 more source
An Introduction to Medical Genetics, 8th edition. By J. A. Fraser Roberts and Marcus E. Pembrey. Oxford University Press. 1985. 394 pages. £11.95. ISBN 0 19 261409 6. [PDF]
, 1986 Eric Reeve
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Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source