C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
American College of Medical Genetics and Genomics ACT Sheets Are a Vital Resource for State Newborn Screening Programs. [PDF]
Sack V+4 more
europepmc +1 more source
20-year experience on prenatal diagnosis in a reference university medical genetics center in Turkey [PDF]
Durmaz B+14 more
europepmc +1 more source
Medical genetics: advances in brief: Couple screening for cystic fibrosis [PDF]
William Reardon
openalex +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Medical Genetics in Brazil in the 21st Century: A Thriving Specialty and Its Incorporation in Public Health Policies. [PDF]
Horovitz DDG, Félix TM, Ferraz VEF.
europepmc +1 more source
The 2019 US medical genetics workforce: a focus on clinical genetics. [PDF]
Jenkins BD+12 more
europepmc +1 more source
Medical genetics: advances in brief: Complete characterization of a large marker chromosome by reverse and forward chromosome painting [PDF]
J. C K Barber
openalex +1 more source
Genetics in the Medical Curriculum
J C Haley, G Gordan Robertson
openaire +4 more sources