Results 61 to 70 of about 1,278,547 (317)

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source

Genetic identification of a common collagen disease in Puerto Ricans via identity-by-descent mapping in a health system

eLife, 2017
Achieving confidence in the causality of a disease locus is a complex task that often requires supporting data from both statistical genetics and clinical genomics. Here we describe a combined approach to identify and characterize a genetic disorder that
Gillian Morven Belbin, Jacqueline Odgis, Elena P Sorokin, Muh-Ching Yee, Sumita Kohli, Benjamin S Glicksberg, Christopher R Gignoux, Genevieve L Wojcik, Tielman Van Vleck, Janina M Jeff, Michael Linderman, Claudia Schurmann, Douglas Ruderfer, Xiaoqiang Cai, Amanda Merkelson, Anne E Justice, Kristin L Young, Misa Graff, Kari E North, Ulrike Peters, Regina James, Lucia Hindorff, Ruth Kornreich, Lisa Edelmann, Omri Gottesman, Eli EA Stahl, Judy H Cho, Ruth JF Loos, Erwin P Bottinger, Girish N Nadkarni, Noura S Abul-Husn, Eimear E Kenny   +31 more
doaj   +1 more source

Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA) [PDF]

, 2009
Background: In this study we aimed to evaluate the role of a SNP in intron 1 of the ERCC4 gene (rs744154), previously reported to be associated with a reduced risk of breast cancer in the general population, as a breast cancer risk modifier in BRCA1 and ...
A Allavena, A Antoniou, A B Spurdle, A C Antoniou, A E Toland, A K Godwin, A Meindl, A Miron, A Osorio, A Osorio, A van den Ouweland, A Viel, A-C Spiess, A-M Gerdes, AC Antoniou, AC Antoniou, B Arver, B Fiebig, B Kaufman, B Malmer, B Versmold, C Casella, C Cassini, C Engel, C F Singer, C I Szabo, C Kiyohara, C Luccarini, C T Oliver, D F Easton, D Ford, D Frost, D G Cruger, D G Evans, D Goldgar, D Gschwantler-Kaulich, D Muller, D Niederacher, D Schaefer, D Stoppa-Lyonnet, D Yannoukakos, DF Easton, DF Easton, E Dagan, E Friedman, E M John, E N Imyanitov, EB Gómez García, F B L Hogervorst, F Douglas, F J Couch, F Lalloo, F Lejbkowicz, F Révillion, G C Rodriguez, G Chenevix-Trench, G Chenevix-Trench, G Pfeiler, G Pichert, G Pita, G Rennert, H Deißler, H Jernström, H Nevanlinna, H Ozcelik, H T Lynch, I L Andrulis, J Basil, J Beesley, J Benítez, J Brunet, J Cook, J F Boggess, J L Hopper, J Simard, J T Wijnen, J-P Fricker, J-P Peyrat, K Claes, K Kosarin, K L Nathanson, K Lange, K Offit, K Wakeley, L Barjhoux, L Foretova, L McGuffog, L Olivier-Faivre, L Tizzoni, LE Mechanic, M A Caligo, M B Terry, M Barile, M Cook, M Daly, M de la Hoya, M Garcia-Closas, M H Greene, M Montagna, M Piedmonte, M S Askmalm, M Thomassen, M Zikan, MM Gaudet, N Arnold, N Ditsch, N Lindor, N Weerasooriya, O Barnett-Griness, O M Sinilnikova, O T Johannsson, P E Schwartz, P J Morrison, P Mai, P Peterlongo, P Radice, R Eeles, R Gershoni-Baruch, R K Schmutzler, R L Milne, R Varon-Mateeva, RL Milne, RL Milne, S Buys, S Chen, S Cohen, S Giraud, S Healey, S Hodgson, S Hooker, S L Neuhausen, S M Domchek, S Manoukian, S Peock, S V Blank, S Verhoef, T Caldes, T Heikkinen, T Kirchhoff, T Kontorovich, T Ramón y Cajal, Thomas v O Hansen, TR Smith, U G Froster, U Hamann, V Moncoutier, V Moreno, X Chen, X Wang, Y C Ding, Y Laitman, Y Yassin   +151 more
core   +4 more sources

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

The Birth of a New Department at MCV/VCU-Human Genetics [PDF]

, 1975
In recognition of the central role of genetics in the health professions, the MCV/VCU School of Basic Sciences and Graduate Studies substantially enlarged its commitment to this discipline by creating a new Department of Human Genetics as of September 1,
Mamunes, Peter
core   +1 more source

The interface between assisted reproductive technologies and genetics: technical, social, ethical and legal issues [PDF]

, 2006
The interface between assisted reproductive technologies (ART) and genetics comprises several sensitive and important issues that affect infertile couples, families with severe genetic diseases, potential children, professionals in ART and genetics ...
ANASTASIADOU V, AYMÉ S, BRAGA S, CORNEL M, COVIELLO, DOMENICO, ESHG, ESHRE, EVERS KIEBOOMS G, GERAEDTS J, GIANAROLI L, HARPER J, IBARRETA D, KÄÄRIÄINEN H, KOSZTOLANYI G, LUNDIN K, RODRIGUES CEREZO E, SEQUEIROS J, SERMON K, SOINI S, TRANEBJAERG L   +18 more
core   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Medical care in clinical genetics: an experience of decentralization in southern Brazil [PDF]

, 2021
Kevin Francisco Durigon Meneghini, Simone de Menezes Karam, Victor Francis Pereira Madruga, Andrea Schulz Silva Ungaretti, Eduarda Cecilia Pinguello, Rafaely Severo   +5 more
openalex   +1 more source

The Growth and Development of Genetics at MCV [PDF]

, 1977
Genetics was well established at the Medical College of Virginia by the time I joined the faculty in 1960. At least one course in genetics was required of students in the Schools of Medicine, Dentistry, Pharmacy, and Nursing.
Townsend, J. Ives
core   +1 more source

The role of the genetic counsellor: a systematic review of research evidence [PDF]

, 2014
In Europe, genetic counsellors are employed in specialist genetic centres or other specialist units. According to the European Board of Medical Genetics, the genetic counsellor must fulfil a range of roles, including provision of information and ...
B Meiser, C Bennett, C Cordier, C James, Caroline Benjamin, Charlotta Ingvoldstad, Christophe Cordier, D Roter, E Pergament, E Smets, H Skirton, Heather Skirton, J Hartley, J Hodgson, J Ingles, JGR Kromberg, JGR Kromberg, KA Hines, KP Powell, L Ellington, LM Kmet, Nicolas Taris, P McCarthy-Veach, R Resta, RG Resta, SJ Lepore, V Braun, V Hannig   +27 more
core   +1 more source