Results 91 to 100 of about 2,275,397 (311)
HISTORY AND WORK OF THE ASSOCIATION OF MEDICAL SUPERINTENDENTS OF AMERICAN INSTITUTIONS FOR THE INSANE—PRESIDENT'S ADDRESS [PDF]
, 1883 John Hancock Callender
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Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
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Актуальні питання суспільних наук та історії медицини, 2016 Skakun I. History of medicine in philosophical and anthropological dimension. The article considers prerequisites of establishment, peculiarities of the content and methodological potential of concept of anthropocentrism in medical history.
Ігор СКАКУН
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An Address ON THE MEDICAL HISTORY OF MR. AND MRS. SAMUEL PEPYS. [PDF]
, 1895 D’Arcy Power
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Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
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Journal of Medical Ethics and History of Medicine Contributors
Journal of Medical Ethics and History of Medicine, 2021 Journal of Medical Ethics & History of Medicine
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Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
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ART. XV.???I. History and Statistics of Ovariotomy, and the Circumstances under which the Operation may be regarded as safe and expedient; being a Dissertation to which the prize of the Massachusetts Medical Society was awarded, May, 1856 [PDF]
GEORGE H. LYMAN
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Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
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