Results 171 to 180 of about 4,852,263 (336)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici+8 more
wiley +1 more source
THE USES OF MEDICAL BIBLIOGRAPHY AND MEDICAL HISTORY IN THE MEDICAL CURRICULUM [PDF]
FIELDING H. GARRISON
openalex +1 more source
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert+13 more
wiley +1 more source
Correlation between clinical features, medical history, and lifestyle factors with colorectal cancer stage. [PDF]
Sghaier A+6 more
europepmc +1 more source
STUDIES OF CRIMINALS. DEGENERACY OF CRANIAL AND MAXILLARY DEVELOPMENT IN THE CRIMINAL CLASS, WITH A SERIES OF ILLUSTRATIONS OF CRIMINAL SKULLS, AND HISTORIES TYPICAL OF THE PHYSICAL DEGENERACY OF THE CRIMINAL.Read in ihe Section of Medical Jurisprudence and Neurology, at the Forty-second Annual Meeting of the American Medical Association, held at Washington, D. C., May, 1891. [PDF]
G Frank Lydston
openalex +1 more source
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf+10 more
wiley +1 more source