Results 201 to 210 of about 2,518,561 (268)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Medical history predicts phenome-wide disease onset and enables the rapid response to emerging health threats. [PDF]

Nat Commun
Steinfeldt J, Wild B, Buergel T, Pietzner M, Upmeier Zu Belzen J, Vauvelle A, Hegselmann S, Denaxas S, Hemingway H, Langenberg C, Landmesser U, Deanfield J, Eils R.   +12 more
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Widely accessible prognostication using medical history for fetal growth restriction and small for gestational age in nationwide insured women. [PDF]

Sci Rep
Sufriyana H, Amani FZ, Al Hajiri AZZ, Wu YW, Su EC.   +4 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Vascular-related cone-beam computed tomographic findings in healthy and medically compromised patients: A study based on self-reported medical history data. [PDF]

Imaging Sci Dent
Damaskos S, Zoukos A, Vlachopoulos C, Angelopoulos C.   +3 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Long-Term Impact of a Medical School Course on the Intersection of Art and Medical History. [PDF]

MedEdPublish (2016)
Coller BG, Slamovits G, Coller BS.
europepmc   +1 more source

Author Correction: Medical history predicts phenome-wide disease onset and enables the rapid response to emerging health threats. [PDF]

Nat Commun
Steinfeldt J, Wild B, Buergel T, Pietzner M, Upmeier Zu Belzen J, Vauvelle A, Hegselmann S, Denaxas S, Hemingway H, Langenberg C, Landmesser U, Deanfield J, Eils R.   +12 more
europepmc   +1 more source

Computer-assisted medical history taking prior to patient consultation in the outpatient care setting: a prospective pilot project. [PDF]

BMC Health Serv Res
Hauber R, Schirm M, Lukas M, Reitelbach C, Brenig J, Breunig M, Brenner S, Störk S, Puppe F.   +8 more
europepmc   +1 more source