Results 251 to 260 of about 10,322,069 (330)

Computer-assisted medical history taking prior to patient consultation in the outpatient care setting: a prospective pilot project. [PDF]

BMC Health Serv Res
Hauber R, Schirm M, Lukas M, Reitelbach C, Brenig J, Breunig M, Brenner S, Störk S, Puppe F.   +8 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Long-Term Impact of a Medical School Course on the Intersection of Art and Medical History. [PDF]

MedEdPublish (2016)
Coller BG, Slamovits G, Coller BS.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Concordance of data collected by an app for medical history taking and in-person interviews from patients in primary care. [PDF]

JAMIA Open
Joos C, Albrink K, Hummers E, Müller F, Antweiler K, Schröder D, Noack EM.   +6 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Mapping and Summarizing the Research on AI Systems for Automating Medical History Taking and Triage: Scoping Review.

J Med Internet Res
Siira E, Johansson H, Nygren J.
europepmc   +1 more source

Medical history and lifestyle factors have limited impact on time-to-first-treatment in patients with chronic lymphocytic leukemia. [PDF]

EJHaem
Glimelius I, Kleinstern G, Robinson DP, Mansouri L, Rostgaard K, Hjalgrim H, Niemann CU, Mattsson M, Rabe KG, Hampel PJ, Parikh SA, Rosenquist R, Cerhan JR, Slager SL, Smedby KE.   +14 more
europepmc   +1 more source

What's the Original Concept of Meridian and Acupuncture Point in Oriental Medicine? - A Perspective of Medical History

, 2005
Shik Yc, K H Gyun
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source