CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Reflections on 'common' genetic medical history questions: Time to examine the what, why, and how. [PDF]
Waltz M +4 more
europepmc +1 more source
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Healthcare leaders' experiences of implementing artificial intelligence for medical history-taking and triage in Swedish primary care: an interview study. [PDF]
Siira E, Tyskbo D, Nygren J.
europepmc +1 more source
Educational Paradigms in Islamic Medical History: A Review.
Asad MR +5 more
europepmc +1 more source
A perfect storm in a pandemic-a child with complex medical history and special diet encounters COVID. [PDF]
Waldrop SW, Krebs NF.
europepmc +1 more source
Modeling for Prediction of Mortality Based on past Medical History in Hospitalized COVID-19 Patients: A Secondary Analysis. [PDF]
Ahmadi SAY +3 more
europepmc +1 more source
Association of Knee Osteoarthritis Treatment Types, Patient Characteristics, and Medical History With Subsequent Risk for Total Knee Arthroplasty: Data From a New Real-World Registry. [PDF]
Concoff AL +11 more
europepmc +1 more source

