Results 41 to 50 of about 13,632,376 (348)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Joint effect of modifiable risk factors on Parkinson’s disease: a large-scale longitudinal study

Frontiers in Human Neuroscience
IntroductionPrevious researches have often underestimated the diversity and combined effects of risk factors for Parkinson’s disease (PD). This study aimed to identify how multiple modifiable risk factors collectively impact PD.MethodsThe study included ...
Panlong Li, Xirui Zhu, Min Liu, Yanfeng Wang, Chun Huang, Junwei Sun, Shan Tian, Yuna Li, Yuan Qiao, Junting Yang, Shanshan Cao, Chaohua Cong, Lei Zhao, Jingjing Su, Dandan Tian   +14 more
doaj   +1 more source

Historical Study on the Construction of Medicinal Knowledge of Areca Catechu L. from the Han Dynasties to the Song Dynasty

Yixue yu zhexue
Focusing on the construction of medicinal knowledge of Areca catechu L., this study systematically examines relevant contents in local chronicles, classics of materia medica texts, medical formularies, and literati notes from the Han Dynasty to the Song ...
Yangchuan YU, Xiujuan DONG, Mei LI
doaj   +1 more source

Children’s psychiatric medical history. Review

European Psychiatry, 2021
Introduction The prevalence of mental disorders in children and adolescents varies between 5 and 22%, depending on the methodology, type of interview, samples and inclusion of the disability criterion.
M.O. Solis, F. Vilchez Español, A. Alvarado Dafonte, M. ValverDe Barea, S. Jimenez Fernandez   +4 more
doaj   +1 more source

De Militis Magni Corpore [PDF]

, 1957
Being an account of the medical history, death and necropsy in the case of the Venerable Ignatius of Loyola (1491-1556), General of the Company of ...
Laforet, Eugene G.
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Von Augusta zu Klingsor, von Luise zu Benjamin – Vergangenheit, Gegenwart und Zukunft der Bibliothek des Instituts für Geschichte der Medizin in Berlin [From Augusta to Klingsor, from Luise to Benjamin – past, present and future of the library of the Institute for the History of Medicine (Berlin)]

GMS Medizin – Bibliothek – Information, 2012
[english] After a brief illustration of the history of the institute, library and archive whose characteristic is in the history of the divided city of Berlin follows the description of the inventory and of the fields of research as well as the tasks the
Scholz, Melanie, Seehausen, Vera
doaj   +1 more source

Integrated Remote Sensing to Assess Disease Control: Evidence from Flat Island Quarantine Station, Mauritius

Remote Sensing, 2022
This article presents an integrated approach used in archaeology and heritage studies to examine health and disease management during the colonial period in the Indian Ocean.
Alessandra Cianciosi, Saša Čaval, Diego Calaon, Krish Seetah   +3 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Using the Chief Complaint Driven Medical History: Theoretical Background and Practical Steps for Student Clinicians

MedEdPublish, 2020
A previous short report presented an approach to teaching a focused medical history in the emergency department by using a chief complaint directed differential diagnosis guided streamlined series of questioning.
Richard J. Nierenberg
doaj