Results 171 to 180 of about 2,598,165 (339)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Instruction in Medical History Taking
Academic Medicine, 1952 S, WOLF, T P, ALMY, J T, FLYNN, F, KERN
openaire +3 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Fibular stress fracture in a female cross-country runner : a case report [PDF]
, 2015 Stress fractures are probably the most feared class of injuries amongst endurance athletes, especially runners, since they require lengthy rehabilitation periods and temporary but drastic modifications of their training regime.
Micallef Stafrace, Kirill +1 more
core
Patients' Attitude towards Medical Students in a Teaching Hospital of Pakistan
Journal of Islamic International Medical College, 2014 Objective: To study patient’s attitude towards medical students on clinical clerkship rotation in a hospital Study Design: Descriptive Cross Sectional Study.
Muhammad Nadim Akbar Khan, Noor Mah Khan, Saadia Sultana
doaj
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Verbal Response Modes in Action:Microrelationships as the Building Blocks of Relationship Role Dimensions [PDF]
, 2013 Dimensions of interpersonal relationships, such as attentiveness, directiveness, and presumptuousness, have typically been assessed through impressionistic ratings or by aggregate scores derived from coding of specific (e.g., verbal) behaviors.
Knobloch-Fedders, Lynne M. +2 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source